Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

Balancing Risk-benefit in Pediatric Nuclear Medicine Far from Childs Play

Professional societies have stepped up efforts to minimize administered activity, based on updated dosage cards and guidelines. Medical physicists recognize that while these protocols are helpful, there is room for improvement.

I-131 Best Practice Or In Need of Use Revision?

Iodine-131 is lauded for its specificity in targeting thyroid lesions. Yet, some experts are debating whether the treatment should be used across the board or stratified.

Targeting Lesion Localization: A New Era

While whole-body oncology imaging advances are still emerging, the best modality remains to be seen.

Coding for Dopamine Transporter Imaging with I-123 Ioflupane

In 2011, the FDA cleared I-123 ioflupane for dopamine transporter imaging, and an SNM expert provides coding advice for Parkinsonian syndromes.

Molecular Imaging of Neuroinflammation in Neurodegenerative Disease

Advancements in molecular neuroimaging are providing new ways to assess neuroinflammation in the brain.

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Spotlight On | Alzheimers Disease

With the aging population, the proliferation of neurodegenerative diseases, particularly Alzheimers, is becoming a truly global burden.

ASNC Releases Dose-Reduction Guidelines for Nuclear Cardiology

Technological improvements in image acquisition and software processing in nuclear cardiology should allow physicians to shave patient imaging times dramatically or cut radiation doses fourfold, according to a new preferred practice statement from the American Society of Nuclear Cardiology (ASNC).

Vulnerable Plaque Imagings Perilous Journey from Bench to Bedside

Revelations about the actual cause of myocardial infarction have led researchers to seek out new ways to diagnose, evaluate, treat and prevent coronary artery disease, specifically through imaging vulnerable plaque.