Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

Molecular subtyping overhauls conventional cancer classification

A powerhouse of genomic information has led to a revamped tumor classification system that reclassifies as many as one out of every 10 cancer cases, according to a meta-analysis published Aug. 7 in the journal Cell.

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First commercial use of Neuraceq beta-amyloid PET

Neuraceq (F-18 florbetaben) became available for commercial use on Aug. 1 and went into action for clinical PET imaging of beta-amyloid in the brain at WVU Healthcare in West Virginia, Piramal Imaging announced today.

Toshiba's new technology enables blood flow visualization never thought possible with ultrasound

Superb micro-vascular imaging helps clinicians deliver a more accurate diagnosis. Toshiba is making it possible for clinicians to use ultrasound to see the smallest vessels in and around areas like tumors and lymph nodes, giving them a new way to diagnose disease faster and non-invasively.

Link between Alzheimer’s and vitamin D deficiency

Low levels of vitamin D are associated with all-cause dementia, including Alzheimer’s disease (AD), according to the largest multicenter population study published Aug. 6 in Neurology. 

African genomics studies get support from NIH

More than $300,000 will go toward genomic research by African investigators carried out in Africa, according to an announcement Aug. 3 from the National Institutes of Health (NIH).

Genomics: The future of medicine

A round up of genomics research is presented in this Telegraph anthology of recent articles from international news sources. Millions of dollars are being funneled into a project to "unlock"  DNA, personal genomics could become second nature, and challenges that have held up the science of genomics and its applications are presented.

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FDG PET finds signs of muscle denervation

A high uptake of FDG could signal glucose hypermetabolism in muscle, making FDG PET a novel addition to more conventional methods of detecting denervation, according to a study published Aug. 7 in the Journal of Nuclear Medicine.

Varian acquires Transpire dose software

Varian Medical Systems announced Aug. 5 that the company acquired dose calculation software produced by Transpire to merge with treatment planning technology.