Reading a 3D thresholded SPECT vs. a conventional 2D SPECT has led to a dramatic improvement in sensitivity for the evaluation of attention deficit hyperactive disorder (ADHD), officials at Amen Clinics announced Dec. 9.

Definiens, the global leader in Tissue Phenomics® for oncology diagnostics, today announced the newest version of its leading image analysis software for quantitative digital pathology, Tissue Studio 4.0. The new release provides greater flexibility, more accurate and consistent results, and the ability to use any chromogen for single and dual stain immunohistochemistry (IHC) quantification.

Genetic research from John Hopkins and the University of Alabama Birmingham are providing a road map of inflammation linked to autism thanks to a fleet of tissue samples from 72 autistic and healthy brains. Analyses of these tissues showed microglial cells in perpetual hyperdrive, which translates into neuro-inflammation.

A readily available antibiotic drug therapy that happens to promote the expression of a certain neurotransmitter receptor could one day be a means of combatting frontotemporal dementia (FTD), officials from the University of Alabama Birmingham announced Dec. 3.

A drug in the same realm as Viagra could treat and perhaps even prevent certain kinds of dementia. Powerful drugs used as a vascular therapy for diabetic patients also may be put to the task, officials from the Alzheimer’s Drug Discovery Foundation (ADDF) and the Alzheimer’s Society UK announced yesterday.

Bavarian Nordic A/S (OMX: BAVA, OTC: BVNRY) announced today that it has reached the planned enrollment of 1,200 patients in the PROSPECT Phase 3 clinical study of its targeted active immunotherapy candidate, PROSTVAC®, in the treatment of asymptomatic or minimally symptomatic metastatic castration-resistant prostate cancer (mCRPC). Patients were enrolled at 214 sites in 15 countries.

One of the biggest challenges in medicine today is getting effective diagnostic and therapeutic drugs through the regulatory process unscathed. Judit Rius, the U.S. manager and legal policy adviser for Doctors Without Borders has words of wisdom to share about how to improve FDA reviews and incentives for the development of treatments for much needed drugs, including those for neglected tropical diseases.

Dual human and preclinical PET scans shine a light on treatments for tuberculosis (TB) and aid in drug discovery and selection, according to researchers at the University of Pittsburgh School of Medicine. University officials announced on Dec. 3 the results of a pivotal study noting that quantitative PET was earmarked for future clinical trials.