Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

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Lightspeed: The Coming of Age of Proton Therapy

Proton therapy used to be the next-generation cancer treatment that was larger than life and too expensive for any institution other than the most cutting-edge research hospital.

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WMIC Looking Ahead to 2015

The 2014 World Molecular Imaging Congress (WMIC) put a spotlight on the basic science and translation of molecular imaging at the World Trade Center in Seoul, South Korea, in September.

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Pancreatic Cancer: Molecular Imaging’s Increasing Role

Currently ranked the fourth-leading cause of cancer-related deaths in the U.S. and slated to move up the list to No. 2 in the next few years, pancreatic cancer has the highest mortality rate and among the poorest prognoses of all major cancers. 

Coqui signs contract with INVAP for Florida isotope facility

Coral Gables, Fla., based Coqui RadioPharmaceuticals is moving forward with designs for a new medical isotope production facility in Alachua, Fla. An agreement to that effect has been signed by INVAP, an Argentine firm specializing in nuclear engineering, Coqui announced Nov. 20.

Lower scan time, dose in SPECT MPI

A new SPECT protocol allows researchers to not only cut scan times down to a quarter of the average time, but it could also be used to lower dose, according to a study published Nov. 20 in the Journal of Nuclear Medicine.

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Alzheimer’s: Untangling the Research

First came the discovery of beta-amyloid plaque as a precursor of cognitive decline, and then came the tangles of tau and wonderment in researchers’ minds as to their relationship.

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Cardiac PET/CT: Measuring calcification via low-dose CT

Low-dose CT has become a mainstay for PET attenuation correction, but why not take it a step further by quantifying coronary artery calcium without adding any extra dose, according to an Ottawa Heart Institute study published ahead of print Nov. 20 in the Journal of Nuclear Cardiology.

A Victory We Aren’t Celebrating—Yet

During my term as president of the Society of Nuclear Medicine (And Molecular Imaging, now appended), we were in the midst of the Molecular Imaging Campaign that was successful in increasing the visibility of nuclear medicine as a measure of physiologic and metabolic parameters in diagnosing our patients.