Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

The case for modernizing biodistribution reporting in nuclear medicine

Radiopharmaceutical dosimetry (RD) is an integral part of nuclear imaging and therapy, but current standards for documenting and reporting compound travel patterns inside the human body—biodistribution—in dosimetry-related studies do not exist.

Monitoring cerebrospinal fluid biomarkers, imaging of brain injuries may identify abnormal neurodevelopment

Monitoring cerebrospinal fluid (CSF) biomarkers and imaging for genetic mediators of brain injuries in children may help identify those at risk for abnormal brain development, according to a study published in the Journal of the American Medical Association.

SPECT/CT may save more than $1.7M over 3 years in total knee replacement surgeries

By 2030, some 3.5 million Americans are expected to be living with total knee replacements. The price of performing total-knee arthroplasty (TKA) revision surgery continues to rise, costing 60 percent more than the initial replacement. Researchers set out to identify a more cost-effective method.

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Diamonds are an MRIs best friend, may increase imaging sensitivity

A new molecular technique using modified diamonds could increase the sensitivity of an MRI and improve patient diagnosis, according to a University of Melbourne press release.

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New molecular imaging approach could aid vast areas of health, disease

A new multimodal imaging approach produced highly-advanced molecular three-dimensional (3D) images of staph infection and may be instrumental in fighting antibiotic resistant infections, according to research published in Science Translational Medicine.

HTG Molecular Diagnostics Announces VERI/O Laboratory Service

TUCSON, Ariz., June 23, 2016 (GLOBE NEWSWIRE) -- HTG Molecular Diagnostics, Inc. (Nasdaq:HTGM), a provider of instruments and reagents for molecular profiling applications, today announced the introduction of its Tucson‑based VERI/O laboratory service, offering laboratory support for its biopharma clients in biomarker research and companion diagnostic development.  The VERI/O laboratory service formalizes and expands HTG’s traditional service offerings, including molecular profiling of retrospective cohorts to support development of targeted and immuno-oncology therapies, building custom research-use-only (RUO) assays to support early stage clinical programs, and developing companion diagnostic assays for use in Phase III registration trials.

MR Solutions offers choice of two preclinical cryogen-free MRI scanner ranges

MR Solutions, which introduced cryogen-free MRI scanners in 2012, is now offering a choice of two cryogen-free preclinical scanner ranges – the Flexiscan and Powerscan. The Flexiscan range is available with multi-modality accessories which can be mixed and matched according to research requirements. It is a flexible MRI system as it can incorporate integrated multi-modality options such as PET or SPECT. The Flexiscan system requires no specialist knowledge and can be operated simply by running pre-defined settings. There is no need to materially alter the parameters of the machine.

Study: Single season of high school football can damage athlete's brain

The repeated impacts experienced in one season of playing high school football can do significant damage to an athlete’s brain, according to a recent study published by the Journal of Neurotrauma.