Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

South African plant leak has caused worldwide medical isotope shortage

South African Nuclear Energy Corp. announced this month that a leak has resulted in a global shortage of molybdenum-99, the precursor for Tc-99m used in a majority of molecular imaging scans. Authorities reportedly conducted an investigation Nov. 12 at the NTP plant in Pelindaba, just shy of 20 miles from the capital of Pretoria. It was estimated that the leak began Nov. 2. and was comprised of noble gas and iodine. Repairs are underway and the NTP plant will await independent review and authorization from the National Nuclear Regulator before operation can begin again.

Quantum dots facilitate a leap into alternative energy

The semiconductor photocatalysts known in molecular imaging as "quantum dots" are now being used for something completely different: alternative energy. The nanocrystals, instead of highlighting tissues, are harnessing methanol through a process of photosynthesis. This and other research, including advances in biomedical 3D printing and oncologic iron-based MRI contrast agents are featured in a profile of new research published in the New York Academy of Sciences magazine.

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PQRS: Play Now or Pay Later

Human nature being what it is, physician participation in Medicare’s Physician Quality Reporting System (PQRS) will likely accelerate as the agency phases incentives out and penalties in. The effect may prove especially conspicuous since the bonuses have been voluntary and modest. By contrast, the forfeitures will be automatic and, if paired with other pay-for-performance requirements, impossible to ignore.

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Imaging Addiction: Could PET & MR End Cocaine Abuse?

Cocaine addiction can ruin a person physically and financially, and with an estimated 1.4 million cocaine users in the U.S., thousands will become trapped by their habit. While previous research on the drug and its addictive potential were observational and subjective, imaging is reshaping how we see addiction—and how it will be treated.

Several new genes found related to Alzheimer's

New research brings 11 new genes into focus as potential links to Alzheimer's and other neurodegenerative diseases including Parkinson's and multiple sclerosis, all associated with the build-up of protein plaques in the brain. The data was made available as a result of the international Genomics of Alzheimer's Project (IGAP), according to an Oct. 28 report by The Huffington Post.

PET captures how social rejection triggers a feel-good reaction

Painful rejection and other social ills prompt the same opioid response in the brain as physical pain, according to new in vivo PET neuroimaigng of snubbed subjects. 

Sofie Bio receives $1.8M SBIR grant for phase II clinical trials

Sofie Biosciences, an emerging in vivo imaging diagnostics company focused on PET probes, scanners and chemistry systems,announced today that the National Institute of Health has awarded the company a grant under the Small Business Innovation Research (SBIR) program.

Philips showcases innovations in radiation oncology imaging technology and workflow planning at the 55th American Society for Radiation Oncology (ASTRO) annual meeting

At the 55th American Society for Radiation Oncology ASTRO annual meeting, Sept. 22-25 in Atlanta, Royal Philips will feature the latest innovations that address efficient and personalized radiation oncology care for patients and their clinicians.