Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography,  RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

Ultrasound societies want the FDA to remove contrast label warning

The International Contrast Ultrasound Society (ICUS) is again urging the FDA to remove the “black box” warning from ultrasound contrast agent (UCA) labels, following its filing of a September 2018 citizen petition with the federal agency.

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MRI, novel contrast agent improves measurement of brain’s calcium activity

The technique, which combines MRI with a manganese-based contrast agent, could help researchers better understand how neurons communicate in the brain, according to the study published online Feb. 22 in Nature Communications.