Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography, RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

Low dose GBCA effective, safe for pediatric imaging
Although gadopiclenol is approved for adults and children ages 2 and older, there is limited data on its use in the pediatric population.
Bayer seeks FDA approval for gadoquatrane, its latest low-dose GBCA
The investigational agent uses 60% less gadolinium without sacrificing image quality, according to recent clinical trial findings.
FDA approves expanded use of 'powerful' lung imaging tool
The approval will make around 1 million more patients eligible to receive the specialized contrast, which enhances the evaluation of lung ventilation.
Cardiac ultrasound contrast completely safe, despite reports to the contrary
There had been a recent uptick in adverse reactions to contrast agents used in transthoracic or stress echocardiography exams, the findings suggest.
FDA approves popular ultrasound enhancing agent for pediatric patients
Unlike other UEA options, GE HealthCare's Optison does not contain polyethylene glycol. The FDA approved its use for adult patients back in 1997.

Contrast shortage update: GE expects supply to 'progressively recover' soon

Production at the facility in Shanghai is expected to be near 100% starting on June 6.

Iodine contrast being loaded into a contrast injector in preparation for a cardiac CT scan at Duly Health and Care in Lisle, Illinois. The contrast shortage is causing some healthcare organizations to postpone exams and procedures and ration contrast supplies. Photo by Dave Fornell

ACR working with FDA and HHS to help address imaging contrast shortage

The American College of Radiology (ACR) announced this week its government relations staff has been engaging federal agencies in an effort to improve product availability and hasten resolution of the ongoing iodine contrast shortage.

Eric Williamson, MD, MSCCT, the president of the Society of Cardiovascular Computed Tomography (SCCT) and professor of radiology at Mayo Clinic, explains how the iodine contrast shortage is causing issues for cardiac CT imaging. He discusses ways imagers can stretch they iodine contrast supplies and some technologies that might help conserve contrast. #contrastshortage

VIDEO: Contrast media shortage impacting cardiac CT imaging

Eric Williamson, MD, president of the Society of Cardiovascular Computed Tomography (SCCT) and professor of radiology at Mayo Clinic, explains how the iodine contrast shortage is causing issues for cardiac CT imaging and ways this can be mitigated.

A comparison between a traditional iodine contrast angiogram (left), and a gadolinium contrast angiogram (right). MRI gadolinium contrast is starting to be used in some interventional radiology procedures and is being considered in interventional cardiology due to the iodine contrast shortage.

Gadolinium can be used as substitute for iodine contrast in some interventional imaging procedures

Gadolinium might be an alternative, stop-gap solution for interventional procedures during the current iodine contrast shortage.

Alan Matsumoto explains gadolinium as substitute for iodine contrast during shortage

VIDEO: Gadolinium being substituted for iodine contrast in some procedures due to shortage

Alan H. Matsumoto, MD, chair of the department of radiology at the University of Virginia, vice chair of the American College of Radiology (ACR) Board of Chancellors, and chairman of the ACR Commission on Interventional and Cardiovascular Radiology, explains that the iodine contrast shortage has led to use of MRI gadolinium contrast agents in some cases.

Kirk Garratt, past SCAI president, explains the impact of the iodine contrast shortage on interventional cardiology and the cath lab. #SCAI

VIDEO: How the iodine contrast shortage is impacting interventional cath labs

Kirk Garratt, MD, medical director of the Center for Heart and Vascular Health, ChristianaCare, and a past president of SCAI, explains what this shortage means for interventional cardiologists.

Addressing contrast media shortage in the short, mid and long term

“We need to commit to changing the supply chain so that a single event in a faraway country does not put us in this predicament again," experts wrote in a new special report shared by Radiology.

GE provides update on contrast media shortage

The COVID lockdowns at the Shanghai plant began on March 31, and although the plant there has since resumed operations, they are not yet at 100% capacity.

Imaging Contrast

Low dose GBCA effective, safe for pediatric imaging

Bayer seeks FDA approval for gadoquatrane, its latest low-dose GBCA

FDA approves expanded use of 'powerful' lung imaging tool

Cardiac ultrasound contrast completely safe, despite reports to the contrary

FDA approves popular ultrasound enhancing agent for pediatric patients