Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography,  RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

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Example of various breast MRI protocol sequences that offer different types of soft tissue enhancement. Imaging performed on a Siemens Magnetom system. Breast MRI can help see through dense breast tissue to better detect cancers. #densebreasts #Breastdensity #BreastMRI

Contrast enhanced breast MRI superior to CEM, but accessibility remains an obstacle

In addition to CE-MRI's increased sensitivity for identifying breast cancers, the researchers also found the modality had superior negative likelihood ratios with higher pre-test probabilities for safely ruling out malignancy. 

An example of spectral cardiac CT being used to show iodine density in the myocardium to show perfusion deficits. Shown by Philips healthcare at ACC 2022.

VIDEO: Mitigating the contrast media shortage impact on CT imaging

Brian Ghoshhajra, MD, MBA, division chief, cardiovascular imaging, Massachusetts General Hospital and associate professor of radiology, Harvard Medical School, explains the impact of the iodine contrast shortage on computed tomography (CT) and cardiac imaging.
 

Contrast shortage update: GE expects supply to 'progressively recover' soon

Production at the facility in Shanghai is expected to be near 100% starting on June 6.

Iodine contrast being loaded into a contrast injector in preparation for a cardiac CT scan at Duly Health and Care in Lisle, Illinois. The contrast shortage is causing some healthcare organizations to postpone exams and procedures and ration contrast supplies. Photo by Dave Fornell

ACR working with FDA and HHS to help address imaging contrast shortage

The American College of Radiology (ACR) announced this week its government relations staff has been engaging federal agencies in an effort to improve product availability and hasten resolution of the ongoing iodine contrast shortage.

Eric Williamson, MD, MSCCT, the president of the Society of Cardiovascular Computed Tomography (SCCT) and professor of radiology at Mayo Clinic, explains how the iodine contrast shortage is causing issues for cardiac CT imaging. He discusses ways imagers can stretch they iodine contrast supplies and some technologies that might help conserve contrast. #contrastshortage

VIDEO: Contrast media shortage impacting cardiac CT imaging

Eric Williamson, MD, president of the Society of Cardiovascular Computed Tomography (SCCT) and professor of radiology at Mayo Clinic, explains how the iodine contrast shortage is causing issues for cardiac CT imaging and ways this can be mitigated.

A comparison between a traditional iodine contrast angiogram (left), and a gadolinium contrast angiogram (right). MRI gadolinium contrast is starting to be used in some interventional radiology procedures and is being considered in interventional cardiology due to the iodine contrast shortage.

Gadolinium can be used as substitute for iodine contrast in some interventional imaging procedures

Gadolinium might be an alternative, stop-gap solution for interventional procedures during the current iodine contrast shortage.

Alan Matsumoto explains gadolinium as substitute for iodine contrast during shortage

VIDEO: Gadolinium being substituted for iodine contrast in some procedures due to shortage

Alan H. Matsumoto, MD, chair of the department of radiology at the University of Virginia, vice chair of the American College of Radiology (ACR) Board of Chancellors, and chairman of the ACR Commission on Interventional and Cardiovascular Radiology, explains that the iodine contrast shortage has led to use of MRI gadolinium contrast agents in some cases.

Kirk Garratt, past SCAI president, explains the impact of the iodine contrast shortage on interventional cardiology and the cath lab. #SCAI

VIDEO: How the iodine contrast shortage is impacting interventional cath labs

Kirk Garratt, MD, medical director of the Center for Heart and Vascular Health, ChristianaCare, and a past president of SCAI, explains what this shortage means for interventional cardiologists.

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