Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

PET/CT in Evolution

PET/CT technology has brought more accurate cancer staging and a drop in scan time to 15 minutes to Karolinska University Hospital/Institute in Stockholm.

Software Fine-tunes Longitudinal Imaging of Cancer

The ease of using one software program to evaluate images from different time points is key to more accurate cancer staging at PET/CT-Zentrum Hamburg in Germany.

SPECT/CT Makes the Grade at the Community Hospital

Crouse Hospital in Syracuse, N.Y., is a 566-bed, acute-care community hospital committed to superior patient care. Its commitment to the community is paralleled by a strong collaborative relationship between its radiology and nuclear medicine departments. 

To the Bone: SPECT/CT Drives Diagnostic Clarity

Torsten Kuwert, MD, of the University of Erlangen, details how new techniques in SPECT/CT are gaining wider acceptance in diagnosing and staging indeterminate bone lesions—in a single patient visit.