Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

Technologists: Hybrid PET/MR is changing the landscape

A new standard is being set for technologists working within the emerging discipline of PET/MR. A meeting of minds from both sides of the technology is necessary to assure a high level of patient care to include diversified education and protocols within the imaging suite, according to a joint consensus statement by the Society of Nuclear Medicine and Molecular Imaging’s Technologist Section (SNMMI-TS) and the Section of Magnetic Resonance Technologists (SMRT) published April 30 in the Journal of Nuclear Medicine Technology.

Amyloid Imaging Task Force revamps appropriate use criteria

The Amyloid Imaging Task Force, a collaborative effort by the Alzheimer’s Association and the Society of Nuclear Medicine and Molecular Imaging (SNMMI), published an update to previous appropriate use criteria for amyloid imaging as it relates to suspected Alzheimer’s disease pathology June 10 in the Journal of Nuclear Medicine.

FDG PET could predict treatment response for major depressives

Previous studies have pointed to treatment-specific imaging biomarkers for predicting response to therapy for patients with major depressive disorder (MDD), but brain imaging with FDG PET, particularly of the anterior insula, is going a step further to differentiate response to combined treatments, which could improve management of patients with the mood disorder, according to a study published June 12 in JAMA Psychiatry.

HHS Releases 2013 Update To The National Alzheimer's Plan

Today, the Department of Health and Human Services (HHS) released the National Plan to Address Alzheimer's Disease: 2013 Update. The first-ever National Alzheimer's Plan, initially released in May 2012, was mandated by the bipartisan National Alzheimer's Project Act (P.L. 111-375), which Congress passed unanimously in 2010. The 2013 Update includes a new timeline for achieving its first goal – prevent and effectively treat Alzheimer's disease by 2025 – and a review of progress over the past year.

PET/MR shows promise for pulmonary nodule evaluation

The launch of PET/MR imaging has renewed interest in the role of MR and PET/MR in pulmonary nodule evaluation. The hybrid modality demonstrated high sensitivity in the detection of FDG-avid nodules and nodules 5 cm or larger, according to a study published online June 4 in Radiology.

IBA Molecular, MIM Software Sign Agreement for PETLinQ Enhancement

IBA Molecular North America, Inc. (IBA Molecular) and MIM Software Inc. (MIM Software™) have announced an agreement to co-develop enhancements to the IBA Molecular PETLinQ™ suite of products.

SNMMI: FDG PET bests MPI in detecting early stage CAD

F-18 FDG PET is superior to stress myocardial perfusion imaging (MPI) in detecting coronary artery disease (CAD), particularly single-vessel disease, according to research presented at the Society of Nuclear Medicine and Molecular Imaging’s 2013 annual meeting in Vancouver.

Stabin at SNMMI: It’s time to take on patient-specific dosimetry

The rally cry heard round the Society for Nuclear Medicine and Molecular Imaging (SNMMI) educational sessions, hallway discussions and exhibit floor pitches this week in Vancouver was the message of Hal Anger Lectureship & Award lecturer Michael G. Stabin, PhD, researcher at Vanderbilt University School of Medicine in Nashville, too: patient-specific dosimetry is a must in diagnosis and therapy. “Patients are different, they need different therapy,” he said.