Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

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Genetic variants may guard against heart disease

Rare protein-truncating variants in the apolipoprotein B (APOB) gene are linked to lower triglycerides and LDL cholesterol levels and also appear to be protective against coronary heart disease (CHD), according to a study published in Circulation: Genomic and Precision Medicine.

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Registry analysis finds link between TAVR volume, mortality

With CMS just months away from an updated national coverage determination for transcatheter aortic valve replacement (TAVR), a new analysis in the New England Journal of Medicine suggests the relationship between procedural volume and TAVR outcomes remains important in the United States.

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FDA approves therapy to reduce infarct size in LAD STEMI after PCI

Once the artery has been opened with PCI, the treatment involves mixing a patient’s own blood with oxygenated saline and then infusing that superoxygenated mixture to the targeted ischemic area for 60 minutes.

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Colorado 2nd state to require surgical smoke evacuation systems

Colorado became the second state to pass legislation requiring surgical smoke evacuation systems at hospitals and ambulatory surgical centers on March 28, when Gov. Jared Polis signed the bill into law. Rhode Island passed a similar law in June 2018.

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White light exposure may hinder recovery for heart patients

An animal study published in Experimental Neurology suggests recovery from cardiac arrest is inhibited by exposure to white light—the same kind that normally illuminates hospital rooms.

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Meta-analysis highlights BP-lowering effect of renal denervation

A meta-analysis of sham-controlled renal denervation trials published in the Journal of the American College of Cardiology found the catheter-based procedure was associated with statistically significant drops in ambulatory and office blood pressure measurements among hypertensive patients.

Apixaban linked to best outcomes in older patients with AFib, heart failure

Compared to warfarin, all direct oral anticoagulants (DOACs) were associated with fewer cardiovascular events including heart attacks and strokes in a study of Medicare patients with both nonvalvular atrial fibrillation and heart failure. But apixaban appeared to offer the best balance of protecting against these events while minimizing bleeding risk.

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Should interventional cardiologists be involved in acute stroke care?

Two papers published March 25 in the Journal of the American College of Cardiology make the case for training other interventionalists, including cardiologists, in performing mechanical thrombectomy to increase access to the emergency stroke treatment.