Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiology, heart failure, electrophysiology, hypertension, structural heart disease, use of pharmaceuticals, and COVID-19.

Moderna, FDA reach compromise to accelerate approval of mRNA flu vaccine
The dispute centered around the pharmaceutical company's request for the shot to be approved for those aged 65 and over, a demographic the FDA argued was not properly represented in a 40,000-person clinical study. The company has agreed to perform additional research after the shot goes to market, having appeased regulators with safety data.
Statin labeling should be revised with updated warnings, meta-analysis confirms
Researchers explored data from more than 123,000 patients, noting that dozens of the adverse complications included on current labels can safely be removed.
Esperion settles another lawsuit to keep generic versions of popular drug off shelves
As soon as Esperion Therapeutics gained FDA clearance for Nexletol in 2020, competitors started trying to copy it. The company is fighting back.
Side effect of popular Alzheimer's treatment may actually be a good sign, new PET findings suggest
Amyloid-related imaging abnormality edema is a known side effect of anti-amyloid monoclonal antibody treatments, such as Leqembi and donanemab Kisunla.
Cardiologist develops new heart device that uses gel to reduce stroke risk in AFib patients
After years of implanting and studying LAAO devices, an interventional cardiologist with the University of Chicago has designed a new alternative that could reduce the risk of bleeding and save health systems money.

Moderna, FDA reach compromise to accelerate approval of mRNA flu vaccine

The dispute centered around the pharmaceutical company's request for the shot to be approved for those aged 65 and over, a demographic the FDA argued was not properly represented in a 40,000-person clinical study. The company has agreed to perform additional research after the shot goes to market, having appeased regulators with safety data.

Statin labeling should be revised with updated warnings, meta-analysis confirms

Researchers explored data from more than 123,000 patients, noting that dozens of the adverse complications included on current labels can safely be removed.

Esperion Therapeutics Inc. has filed patent infringement lawsuits against eight generic drug makers for filing U.S. Food and Drug Administration (FDA) abbreviated new drug applications (ANDA) to make generic versions of its successful bempedoic acid (Nexletol).

Esperion settles another lawsuit to keep generic versions of popular drug off shelves

As soon as Esperion Therapeutics gained FDA clearance for Nexletol in 2020, competitors started trying to copy it. The company is fighting back.

Side effect of popular Alzheimer's treatment may actually be a good sign, new PET findings suggest

Amyloid-related imaging abnormality edema is a known side effect of anti-amyloid monoclonal antibody treatments, such as Leqembi and donanemab Kisunla.

After years of implanting left atrial appendage occlusion (LAAO) devices in atrial fibrillation (AFib) patients, an interventional cardiologist with the University of Chicago Medical Center (UChicago Medicine) has developed a new device that could be a more affordable alternative to Boston Scientific’s Watchman and Abbott’s Amplatzer Amulet LAA Occluder.

Cardiologist develops new heart device that uses gel to reduce stroke risk in AFib patients

After years of implanting and studying LAAO devices, an interventional cardiologist with the University of Chicago has designed a new alternative that could reduce the risk of bleeding and save health systems money.

PAD patients could be missing out on recommended care following major lower extremity amputations

Patients undergoing the procedures due to infection, chronic limb-threatening ischemia and other serious complications may not be receiving the follow-up care their need.

Michael Honigberg, MD, MPP, a preventive cardiologist and cardiovascular researcher at Massachusetts General Hospital, explains how preeclampsia and gestational hypertension during pregnancy can elevate cardiovascular risks later in life and how to best manage these patients.

How hypertension during pregnancy impacts a woman's long-term cardiovascular health

Emerging research suggests that the early postpartum period may represent a critical window for influencing a woman's long-term cardiovascular health.

Rosabella Moringa FDA recall supplement salmonella

FDA investigating outbreak of ‘extensively’ antibiotic resistant salmonella linked to supplement

Capsules of moringa tree leaf, branded as Rosabella, are being recalled after seven states report cases of the illness, with three patients saying they took the supplement. The company has issued an emergency recall.