Researchers with LSU Health New Orleans School of Medicine believe they’ve discovered a molecular explanation for why hypoxia increases the risk for blood clots.

Lowering LDL cholesterol (LDL-C) beyond guideline-recommended levels further reduces cardiovascular events without compromising safety, according to a meta-analysis published Aug. 1 in JAMA Cardiology.

More than three-fourths of patients who received percutaneous balloon mitral valvuloplasty (PBMV) at a center in Brazil maintained procedural benefit over a median follow-up of 8.3 years, researchers reported in JACC: Cardiovascular Interventions.

A protein known to protect brain function in the setting of Duchenne muscular dystrophy may also have a positive impact on the heart, according to preliminary research presented at the American Heart Association’s Basic Cardiovascular Sciences scientific sessions on Aug. 1 in San Antonio.

Continually updated mortality models based on adverse events and end-organ function are better at showing which transplant candidates most urgently require a new heart, according to a study published in the Journal of the American College of Cardiology.

Researchers have developed an online tool to more accurately calculate which middle-aged individuals are at the highest risk of heart attack or stroke during the next 10 years.

A simple measure of waist circumference could identify chronic heart failure patients who would benefit most from mineralocorticoid receptor antagonists, according to a review published July 25 in JAMA Cardiology.

In following patients with heart failure for up to 15 years, Spanish cardiologists found left ventricular ejection fraction (LVEF) followed an inverse U-shape: LVEF improved for the first year, then plateaued for the rest of the first decade and declined in the following years—especially before death.