Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

Ticagrelor reversal agent receives FDA breakthrough therapy designation

The FDA has granted a breakthrough therapy designation to a novel reversal agent for ticagrelor called PB2452, PhaseBio Pharmaceuticals announced April 8.

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Younger-onset diabetes linked to most extreme CVD risks

People diagnosed with type 2 diabetes at 40 or younger were about twice as likely to die over 5.6 years of follow-up compared to age-matched controls, according to a registry study from Sweden. But the relationship weakened substantially as the age of onset progressed, such that patients diagnosed in their 80s carried no excess mortality risk.

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Thrombectomy offers survival benefit for acute stroke

Endovascular thrombectomy (EVT) significantly reduced the risk of 90-day mortality in patients with acute ischemic stroke compared to medical therapy alone, according to a meta-analysis of 10 randomized trials cited in the 2018 update to American stroke guidelines.

The risks, benefits of polypharmacy after MI for frail nursing home residents

Nursing home residents who were prescribed three or four preventive medications after myocardial infarction (MI) were 26% less likely to die within 90 days than those prescribed only one drug, researchers reported April 9 in Circulation: Cardiovascular Quality and Outcomes.

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Comic illustrations enhance informed consent before coronary angiography

A new pilot study out of Germany suggests a comic-style graphic supplement can improve the informed consent process before coronary angiography by putting patients at ease and helping them understand the procedure.

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Socioeconomic factors may impact the chances of getting an LVAD

A study of nearly 900,000 patients with heart failure or cardiogenic shock revealed their race, insurance coverage and ZIP code were associated with their odds of receiving a left ventricular assist device (LVAD).

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Medtronic, Blue Cross ink outcomes-based agreement for glucose monitor

Medtronic has struck a value-based agreement with Blue Cross and Blue Shield of Minnesota in which the medical device company will pay back the insurer if patients using the Guardian Connect continuous glucose monitoring (CGM) system fail to keep their blood sugar levels within a specified range.

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Real-world Watchman results hold up at 2 years

Left atrial appendage (LAA) closure with the Watchman device was associated with low rates of stroke and bleeding events in high-risk atrial fibrillation patients over a two-year follow-up period, according to a real-world analysis published April 3 in Circulation: Electrophysiology and Arrhythmia.