Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Patients with 'broken heart syndrome' twice as likely to experience complications if they’ve had cancer

Cardiac patients diagnosed with “broken heart syndrome” are twice as likely to run into clinical complications during treatment if they have a history of cancer, Italian researchers reported this week at the ESC Congress in Munich.

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Tafamidis shows promise for treating cardiac amyloidosis

Research presented this week at the European Society of Cardiology Congress in Munich suggests a new treatment may be emerging for transthyretin amyloid cardiomyopathy—a condition previously thought to be rare and untreatable.

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Staff shortage prompts suspension of Oregon’s lone heart transplant center

Oregon’s only heart transplant program has suspended operations for at least two weeks after three cardiologists either left or announced plans to leave Oregon Health & Science University, The Oregonian reported Aug. 27.

Review: Heart failure trials lack women, older patients

Although heart failure researchers have made strides in enrolling more racial and ethnic minorities in clinical trials, women and older patients remain underrepresented, according to a systematic review published in JAMA Cardiology.

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Researchers unveil genetic variants related to heart failure outcomes in blacks

A new study in JAMA Cardiology uncovered a set of genetic variants that are almost exclusive to people of African ancestry and may explain their higher risk of adverse events related to dilated cardiomyopathy (DCM).

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FDA: Temporary artificial heart linked to excess mortality, stroke risk

The FDA on Aug. 17 sent a letter warning cardiologists about high mortality and stroke rates associated with the Temporary Total Artificial Heart (TAH-t) Companion 2 Driver System during a post-approval study.

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How deadly is Takotsubo syndrome? It depends on the trigger

Originally thought to be a benign condition, Takotsubo syndrome is associated with long-term outcomes similar to acute coronary syndrome (ACS), researchers reported in the Journal of the American College of Cardiology. And in cases where Takotsubo syndrome (TTS) is triggered by physical events, prognosis is even worse.

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Researchers ID potential genetic marker for tachycardia-induced cardiomyopathy

Japanese researchers believe they’ve identified a genetic risk marker that could pinpoint which people with atrial fibrillation (AFib) are at risk of developing tachycardia-induced cardiomyopathy.