Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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FDA wants new heart damage warnings added to COVID-19 vaccines

COVID-19 vaccines are associated with a very low risk of myocarditis and/or pericarditis, primarily in young adults. The long-term impact of this risk has been the subject of many studies and debates over the years; one side says that the benefits of vaccination far outweigh the risks, and the other side says that even the smallest risk of heart damage is too high.

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2 out of 5 heart failure patients are not seeing a cardiologist

Even seeing a cardiologist once per year can help these patients elevate their long-term survival. Many stay home, however, missing out on potentially life-saving guidance and/or treatment.

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Duke specialists to detail the benefits of treating heart failure with Barostim

Specialists with Duke University Medical System will participate in a free webinar focused on their experience treating heart failure with the implantable Barostim technology from CVRx.

Many attendees shot selfies in front of the the massive heart on display in the Cytokinetic booth at AHA 2022.

New drug for obstructive HCM outperforms the current standard of care

Cytokinetics announced positive results from a new clinical trial comparing aficamten monotherapy to the beta blocker metoprolol.

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Smaller LV dimensions may increase risk of death for HeartMate 3 LVAD patients

Researchers tracked short- and long-term data from nearly 2,000 patients, presenting their findings in JACC: Heart Failure

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Tirzepatide bests semaglutide in patients with type 2 diabetes, kidney disease and heart failure

Researchers examined data from more than 9,000 patients, sharing their findings at SCAI 2025.

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Consistent cannabis use linked to multiple cardiovascular risks for heart failure patients

Cannabis use can be especially harmful for heart failure patients, according to new data presented at SCAI 2025.

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Sterile, temperature-controlled preservation reduces long-term mortality after heart transplant by 54%

An advanced preservation system from Paragonix, a Getinge company, was linked to dramatic reductions in both mortality and procedural complications.