Will operators be able to replicate COAPT’s restraint and its outcomes?

Compared to drug therapy alone, catheter ablation nearly halved the risk of death and improved a range of clinical outcomes for patients with both heart failure and atrial fibrillation (AFib) in a meta-analysis.

Popular anti-diabetes drug metformin could have positive implications for heart failure patients, too, according to a recent study that found the medication reduced left ventricular stiffness in mice with heart failure with preserved ejection fraction (HFpEF).

Although efforts to reduce heart failure (HF)-related deaths and readmissions in the United States were successful in the early 2000s, rates of HF-related ER visits, comorbid hospitalizations and mortality are at a standstill in 2018, according to a nationwide study published Dec. 11 in Circulation: Heart Failure.

Two baboons recently survived for six months following the transplantation of genetically modified pig hearts, bringing scientists closer to potentially using animal organs for humans who need transplants.

University of Pennsylvania researchers have developed a stem cell-based test to determine whether genetic variants in heart muscle cells are benign or pathogenic. In other words, they’ve added some certainty to variants of uncertain significance—the tricky alleles that can either contribute to the development of diseases or be completely harmless.

Receiving the flu vaccine could improve cardiovascular and all-cause mortality outcomes in patients with heart failure, according to a large-scale study of Danish citizens published Dec. 10 in Circulation.

A study presented Dec. 6 at the EuroEcho-Imaging 2018 conference in Milan adds to the debate over the "obesity paradox," finding that acute heart failure patients with a body mass index (BMI) of 23 or higher had better survival over nearly three years of follow-up than those with a BMI below that threshold.