Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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Physicians weigh the efficacy, risk of the Impella pump

Use of the Impella heart pump during PCI rose rapidly between the 2000s and 2010s, according to a Circulation analysis—but so did its variability across hospitals and associated adverse outcomes.

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Transcatheter HF device receives breakthrough designation from FDA

The FDA has granted Breakthrough Device status to BioVentrix, Inc.’s Revivent TC Transcatheter Ventricular Enhancement System, a proactive approach to treating MI-induced heart failure.

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Bionic pacemaker could reverse-remodel hearts affected by HF

A novel pacemaker designed to mimic a patient’s organic breath increased blood flow to the heart in a study of individuals with heart failure, according to research published in the journal Thorax.

New approach emerges for treating HF patients with and without diabetes

Patients with heart failure and reduced ejection fraction are well served by treatment with the glucose-lowering drug dapagliflozin, as it warded off death and hospitalization while also improving quality of life when added to standard care regimens in a major trial.

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AI tool predicts HF mortality with 88% accuracy

A collaboration between physicists and cardiologists at the University of California San Diego has resulted in an AI tool that can predict heart failure patients’ life expectancy with 88% accuracy.

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1st major study of hypertrophic cardiomyopathy offers clues about the elusive disease

Results from the world’s largest comprehensive study of hypertrophic cardiomyopathy patients are in—and they’re providing cardiologists with a wealth of previously unknown information about the disease.

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HF mortality on the rise due to rapidly aging population

The 2010s saw a decrease in age-adjusted mortality associated with heart disease, according to a JAMA Cardiology report, but a concomitant rise in heart failure-related deaths and increase in the global population of adults over 65 actually resulted in an increase in the number of fatalities attributed to CVD.

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Many HF patients prescribed meds that could worsen their condition

Research published in JACC: Heart Failure Nov. 6 uncovered a worrying statistic in cardiology: Older patients who are hospitalized for heart failure could experience as much as a 12% increase in the number of HF-exacerbating medications they’re prescribed between admission and hospital discharge.

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