Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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Beta-blocker use benefits patients with HFrEF and chronic kidney disease

However, these trends do not appear to be true for all heart failure patients. 

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COVID-19 patients with a history of heart failure face considerably worse outcomes

In-hospital mortality, myocardial injury and acute kidney injury were all more common when patients with a history of heart failure tested positive for COVID-19. 

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How much is too much? Older heart failure patients often go home on 10 or more prescriptions

Clinicians should consider the potential negative impact of prescribing so many medications at once, the study's authors noted. 

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A breakthrough on the horizon: Humans could begin receiving transplanted pig hearts by 2021

A longtime goal for cardiac surgeons now appears to be within reach, according to researchers out of Massachusetts General Hospital.

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SGLT2 inhibitors associated with consistent cardiovascular benefits

The study's authors explored data from six different randomized, placebo-controlled trials.

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How treating AFib with catheter ablation affects patients with heart failure

One key finding reported by the research team was a substantial decrease in AFib readmissions. 

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Chemotherapy could be damaging children’s heart cells, leading to problems later in life

The researchers think their findings may explain why so many cancer survivors go on to experience heart failure.