Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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Empagliflozin reduces risk of cardiovascular death, hospitalization among heart failure patients

The EMPEROR-Reduced trial included data from more than 3,700 adult patients with HF and a left ventricular ejection fraction of 40% or less.

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Combination of hydroxychloroquine and azithromycin can induce CV mortality, heart failure

The meta-analysis included data from more than 950,000 patients.

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Healing damaged hearts: New breakthrough could change cardiac care as we know it

Chemists have uncovered a new technique that could make it possible to heal a patient’s damaged heart tissue after a myocardial infarction (MI).

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AI and imaging help answer a cardiac mystery centuries in the making

Trabeculae, detailed networks of muscle fibers on the heart, were first sketched by Leonardo da Vinci 500 years ago. He wondered what they were and what, exactly, they did.

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Why older patients are especially vulnerable to heart damage from COVID-19

COVID-19 enters a person’s heart cells by attacking certain proteins—and when more of those proteins are present, the virus has more chances to cause damage.

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Policy update: CMS proposes expanded coverage for artificial hearts, LVADs

The proposed changes, announced August 12, are focused on easing a variety of requirements.

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Pupil measurements predict all-cause mortality among heart failure patients

The study's authors explored data from 870 acute heart failure patients treated at the same facility from January 2012 to December 2017.

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Cardiovascular research taking a hit during pandemic

As the COVID-19 pandemic continues, researchers have been forced to put important projects on hold—and it’s unclear when things will return to normal.