Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

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U.S. heart failure data includes encouraging signs, reasons for concern

The analysis, published in JAMA Network Open, included data from nearly 1.8 million Medicare patients. 

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Catheter ablation improves LVEF, boosts survival for heart failure patients with atrial fibrillation

Catheter ablation was consistently linked to more substantial LVEF improvements than pharmacological therapy.

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Vericiguat ineffective for patients with worsening HFpEF

The analysis included data from nearly 800 patients with a history of chronic heart failure. 

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Beta-blocker use benefits patients with HFrEF and chronic kidney disease

However, these trends do not appear to be true for all heart failure patients. 

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COVID-19 patients with a history of heart failure face considerably worse outcomes

In-hospital mortality, myocardial injury and acute kidney injury were all more common when patients with a history of heart failure tested positive for COVID-19. 

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MitraClip an effective bridge strategy for advanced heart failure patients waiting for a heart transplant

The findings were presented Friday, Oct. 16, at TCT Connect 2020.

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How much is too much? Older heart failure patients often go home on 10 or more prescriptions

Clinicians should consider the potential negative impact of prescribing so many medications at once, the study's authors noted. 

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A breakthrough on the horizon: Humans could begin receiving transplanted pig hearts by 2021

A longtime goal for cardiac surgeons now appears to be within reach, according to researchers out of Massachusetts General Hospital.