Clinical Research

New gene therapy may help protect the hearts of patients with Friedreich's ataxia
A majority of deaths from Friedreich's ataxia are associated with heart complications. A new treatment years in the making could provide some much-needed relief.
Long-term cardiac amyloidosis survival benefits seen in extension acoramidis trial
Patient outcomes clearly show acoramidis reduces both all-cause mortality and cardiovascular hospitalizations, but the study also reinforced the importance of early diagnosis and prompt medical therapy.
FDA clears way for IDE pivotal trial of the Topaz tricuspid valve replacement system
The TRiCares Topaz uses a unique two-stent frame valve prosthesis for better sealing and flexibility.
Deepak Bhatt discusses some of the most impactful trials at ACC 2026
Bhatt describes a mix of drug, device and strategy trials pointing to advances in cardiovascular science.
Screening and treatment for chronic kidney disease in heart disease patients needs to be expanded
The risk associated with under-recognized CKD emerged early, highlighting the need for screening soon after a CAD diagnosis so that cardio-renal protective drugs can be started much earlier.

Could diamond dust replace gadolinium in MRI contrast agents?

An accidental discovery could have future implications for the material makeup for MRI contrast media.

Statin therapy may help HFpEF patients lower their risk of death, heart attack or stroke

All participants were free of ASCVD and had no history of statin use at the start of the study.

New PET technique spots 'smoldering' changes not visible on MRI in the brains of MS patients

The new technique uncovers hidden inflammation in patients who, despite undergoing extensive treatment for the condition, had worsening symptoms.

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TAVR, SAVR linked to similar QOL improvements for intermediate-risk patients after five years

TAVR was initially associated with greater benefits than surgery, but that difference faded by the end of the first year.

Rad techs helpfully ‘stand in a surgeon’s shoes’ thanks to virtual reality

Johns Hopkins researchers demonstrated the worthiness of the concept this year.

Video of James Januzzi explaining the results of a new diabetic cardiomyopathy treatment in ACC 2024 late-breaking ARISE-HF trial. #ACC #ACC24 #ACC2024

Diabetic cardiomyopathy treatment shows promise in ARISE-HF

James Januzzi Jr., MD, said the treatment's overall impact was neutral, but he and his team saw "a very clear and encouraging signal."

Alzheimer’s imaging experts to assess utility, efficiency of Hyperfine’s Swoop system

Is portable MRI suitable for finding abnormalities in the brains of patients receiving new amyloid-targeting therapy for Alzheimer’s disease? Clinical researchers are about to find out.

Video of Alexander Fanaroff explaining the details of the BE ACTIVE trial that gamified fitness for cardiac patients. #ACC #ACC24 #ACC2024

Motivation helps heart patients stay active

Alexander Fanaroff, MD, said the late-breaking BE ACTIVE clinical trial presented at ACC.24 offers a blueprint for how to get patients to be more physically active.

Clinical Research

New gene therapy may help protect the hearts of patients with Friedreich's ataxia

Long-term cardiac amyloidosis survival benefits seen in extension acoramidis trial

FDA clears way for IDE pivotal trial of the Topaz tricuspid valve replacement system

Deepak Bhatt discusses some of the most impactful trials at ACC 2026

Screening and treatment for chronic kidney disease in heart disease patients needs to be expanded