Clinical Research

Artificial intelligence (AI) is being developed to help make cardiovascular clinical trials more efficient, lead to faster advances in patient care, and bring possible new treatments to heart patients more quickly. The major cardiac research center of Icahn School of Medicine at Mount Sinai announced today that it signed a memorandum of understanding with the Chiba Institute of Technology (CIT) to collaborate on using AI to enhance cardiovascular disease research.

Mount Sinai partners with the Chiba Institute of Technology on AI to transform cardiovascular research 

Agreement aims to use AI to help make cardiology clinical trials more efficient and lead to faster advances in patient care. 

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Complex PCI among older patients linked to increased risk of death

“Given the dramatic difference in death risk for older adults receiving complex PCI, we suggest that such interventions in this exceptionally vulnerable population should be approached with additional caution," researchers wrote. 

Merck is seeking FDA approval for sotatercept to be used as a treatment for pulmonary arterial hypertension

FDA grants speedy review to Merck's new drug for pulmonary arterial hypertension

The FDA is expected to base its decision in part on the STELLAR clinical trial, which included 163 adult patients treated with subcutaneous sotatercept and 160 patients treated with a placebo.

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Radiologists deliver fewer false-positive results than advanced AI models

A new study out of Denmark reveals humans have a definite advantage when a diagnosis requires real-world experience. 

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FDA approves empagliflozin for treating chronic kidney disease

The popular SGLT2 inhibitor, sold by Boehringer Ingelheim and Eli Lilly and Company under the name Jardiance, has already been approved by the FDA to treat type 2 diabetes and heart failure.

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GPT-4 unlocks key insights from free-text radiology reports

Both ChatGPT and GPT-4 were found to be be good at analyzing free-text notes for lung cancer insights. One of the two programs, however, was able to outperform the other.

How MRI “fingerprinting” could help personalize breast cancer treatment

Researchers from Case Western Reserve University are commissioning a study to determine if a novel MRI technique can predict the effectiveness of chemotherapy in treating breast cancer.

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Patients admitted with C. diff not a significant source of in-hospital transmission

Hospital patients who test positive for Clostridioides difficile immediately upon admission but show no symptoms are highly unlikely to spread the germ to other inpatients.