pharmaceutical drug approval process

New drug candidate for AFib fails in first-in-human trial—in fact, it made matters worse

Researchers had thought 2-HOBA might reduce the risk of AFib recurrence after catheter ablation procedures. What they found, however, was that treatment with the compound was actually harmful for patients instead of helpful. 

John D. Puskas, MD, MSc, PhD., FACS, FACC, professor of surgery, and chief of cardiothoracic surgery at Emory University Hospital Midtown, explains when patients are best served with coronary artery bypass graft (CABG) surgery rather than percutaneous coronary intervention (PCI).

How to choose between CABG and PCI when treating coronary artery disease

John Puskas, MD, chief of cardiothoracic surgery at Emory University Hospital Midtown, noted that both treatment options have their own benefits. It often depends on the patient's age and comorbidities, though there are other factors to consider as well. 

Joshua Joseph, MD, MPH, FAHA an expert in Cardiovascular-Kidney-Metabolic (CKM) syndrome, associate professor of internal medicine, and the Endowed Professor for Research in Internal Medicine in the Division of Endocrinology, Diabetes and Metabolism at The Ohio State University Wexner Medical Center, explains the CKM advisory from the American Heart Association designed to help define and stage the disease. CKM has seen a large amount of growing interest from cardiologists in recent years.

Interest rising in CKM syndrome as connections become clearer

Cardiovascular-kidney-metabolic (CKM) syndrome is a popular research topic among cardiologists, highlighting just how closely obesity, type 2 diabetes, chronic kidney disease and cardiovascular disease are related to one another. Joshua Joseph, MD, spoke to Cardiovascular Business about this ongoing trend.

The use of intravascular lithotripsy (IVL) during percutaneous coronary intervention (PCI) is still safe and effective when patients present with calcified nodules (CNs), according to new long-term data published in EuroIntervention.[1] Researchers compared outcomes from patients with and without CNs, highlighting key similarities in stent expansion and luminal gain.

Complications after intravascular lithotripsy are rare, real-world data confirm

Shockwave Medical, now a part of Johnson & Johnson MedTech, has consistently been found safe for patients. However, many previous clinical trials excluded high-risk patients, making it important to track real-world outcomes as time goes on.

Newsweek ranked the 50 best heart hospitals in the world

‘This trend is encouraging’: Radial access for PCI now preferred in US

In fact, more than 55% of all PCI cases in 2022 were performed using radial access. Cardiologists are sure to be keeping a close eye on this trend as time goes on.

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Widespread use of polypills could prevent up to 72 million heart disease deaths

Targeting high-risk patients with single-pill combination therapies, also known as polypills, could change healthcare on a global scale, according new data published in the Journal of the American College of Cardiology

Video interview with Allen Taylor, MD, chairman of cardiology at Medstar, who explains use of AI CCTA plaque analysis at Medstar to improve risk assessments.

AI software takes cardiac risk assessments to another level

Allen Taylor, MD, thinks AI-powered plaque evaluations can make a substantial impact on patient care. 

heart surgery cardiac surgeons

How pairing SAVR with additional heart surgeries affects mortality risk

When older patients undergo SAVR with concomitant procedures, it increases their short- and long-term risks of mortality. Should this influence care teams to consider more transcatheter treatments?