Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

Thumbnail

NIH hands out $3.5M grant for PET-based research into depression

Stony Brook University investigators seek to quantify the precise degree of brain inflammation in those with the illness and ultimately hope to suggest novel treatments.

Thumbnail

Researchers ID potentially treatable genetic mutation target for therapy-resistant prostate cancer

German scientists found six of seven patients with difficult-to-treat cancer had genetic mutations in their DNA damage-repair genes, according to new research.

Thumbnail

Global medical isotope company secures $19M to ‘revolutionize’ nuclear medicine industry

Vancouver, British Columbia-based Artms will use the funding to help bolster the supply of locally produced radioisotopes, such as technetium-99m.

Thumbnail

Hospitals should be required to report adverse radioisotope injections, expert argues

Inflitration occurs when a a radiotracer is not safely injected into an individual's vein, but the true impact of these adverse events remains unknown to patients and physicians.

New PET imaging approach depicts widespread damage of early Alzheimer’s

A novel radiotracer and synaptic imaging revealed "widespread" losses throughout the brain, Yale University researchers reported Wednesday.

Thumbnail

Australian reactor produces new radioisotope with potential to enhance molecular imaging

The Australian Nuclear Science and Technology Organization said its new scandium-47 radioisotope has applications in both PET and SPECT approaches.

Thumbnail

Digital PET/CT roots out smaller cancers with quicker imaging times

Clinicians using this modern machine can get a more accurate contrast measurement and improve their cancer diagnosis, researchers wrote in the Journal of Nuclear Medicine.

Thumbnail

PSMA PET/CT tops conventional imaging for pinpointing high-risk cancer

Australian researchers also recommended updating current diagnostic pathways to incorporate the new molecular imaging approach.