Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography, RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

Bayer's MR contrast injection system cleared by FDA for expanded use
The updated clearance expands the system's labeled field strength compatibility; the change will allow MRI suites with scanners up to the 7T range to utilize the system.
FDA approves expanded use of gadolinium-based imaging agent
Gadopiclenol is a macrocyclic high-relaxivity GBCA that contains less than half the amount of gadolinium that standard agents are formulated with.
Bayer: Aiding Customer Resilience Amid CT Disruption
U.S. Radiology departments navigating CT market challenges—supply disruptions and rising demand for contrast and delivery—need reliable partners. Hear Bayer leads explain how Bayer helps provide steady supply and innovations to support CT imaging and patient care.
New oral contrast agent helps spot 'previously impossible-to-detect' findings on CT
Experts involved in its development are confident the agent has the potential to overcome shortcomings associated with conventional oral agents currently on the market.
Prominent organizations endorse new contrast-enhanced ultrasound curriculum and training
The endorsement follows recent program updates, implemented following an expansion to the Scope of Practice and Clinical Standards for the Diagnostic Medical Sonographer.

Carbon dioxide a safe, effective contrast alternative for vascular procedures

Researchers believe that it could be especially beneficial in patients with impaired kidney function who may be at risk of adverse reactions to standard ICM.

Contaminated CT contrast blamed for 8 patient hospitalizations

After several radiology patients were sickened following an injection of iodinated contrast, the hospital where the incidents occurred has revealed the culprit.

Lowest dose gadolinium-based contrast agent to date inches closer to FDA approval

Gadoquatrane is now set to go through the regulatory review process on its trek to earning full FDA approval.

Woman dies following severe allergic reaction to CT contrast

The 22-year-old patient was undergoing a computed tomography exam with contrast due to her history of kidney stones.

Fluorescent contrast agent helps diagnose basal cell carcinoma.

Fluorescent contrast agent noninvasively identifies common skin cancer

When used topically, the agent penetrates the skin and generates a fluorescent signal under the guidance of a fluorescent confocal microscope.

Bacteria-based contrast agent lights up tumor margins significantly better than other agents.

Bacteria-based contrast agent offers 'substantial improvements' for tumor border delineation during surgery

Essentially, the agent places a bright neon sign on the entirety of tumors and their borders, and it does so autonomously.

Low dose GBCA effective, safe for pediatric imaging

Although gadopiclenol is approved for adults and children ages 2 and older, there is limited data on its use in the pediatric population.

Bayer seeks FDA approval for gadoquatrane, its latest low-dose GBCA

The investigational agent uses 60% less gadolinium without sacrificing image quality, according to recent clinical trial findings.

Imaging Contrast

Bayer's MR contrast injection system cleared by FDA for expanded use

FDA approves expanded use of gadolinium-based imaging agent

Bayer: Aiding Customer Resilience Amid CT Disruption

New oral contrast agent helps spot 'previously impossible-to-detect' findings on CT

Prominent organizations endorse new contrast-enhanced ultrasound curriculum and training