Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography, RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

Low dose GBCA effective, safe for pediatric imaging
Although gadopiclenol is approved for adults and children ages 2 and older, there is limited data on its use in the pediatric population.
Bayer seeks FDA approval for gadoquatrane, its latest low-dose GBCA
The investigational agent uses 60% less gadolinium without sacrificing image quality, according to recent clinical trial findings.
FDA approves expanded use of 'powerful' lung imaging tool
The approval will make around 1 million more patients eligible to receive the specialized contrast, which enhances the evaluation of lung ventilation.
Cardiac ultrasound contrast completely safe, despite reports to the contrary
There had been a recent uptick in adverse reactions to contrast agents used in transthoracic or stress echocardiography exams, the findings suggest.
FDA approves popular ultrasound enhancing agent for pediatric patients
Unlike other UEA options, GE HealthCare's Optison does not contain polyethylene glycol. The FDA approved its use for adult patients back in 1997.

The new MRI contrast agent gadopiclenol, sold under the trade names Elucirem and Vueway by Bracco and Guerbet, used 50% less gadolinium that current MRI agents. #RSNA22 #RSNA

New contrast agent earns positive safety classification from ACR

The ACR Committee on Drugs and Contrast Media stated that exposure to the gadolinium-based contrast agent represents a “sufficiently low or possibly nonexistent” risk to patients.

New data suggest clinicians should think twice before foregoing contrast-enhanced imaging

The new data highlight a potential pitfall of unenhanced CT scans on patients presenting to emergency departments with acute pain—an inaccurate workup.

ACR applauds FDA about-face on use of iodinated contrast in children

The update marks a change from the FDA's stance on the topic last year.

CCTA with patient-specific versus fixed post-trigger delay

Patient-specific versus fixed post-trigger delay: Which offers superior CCTA image quality?

New research compares peak enhancement timing of a patient-specific post-trigger delay and a fixed delay during CCTA.

Iodine contrast being loaded into a contrast injector in preparation for a cardiac CT scan at Duly Health and Care in Lisle, Illinois. The contrast shortage is causing some healthcare organizations to postpone exams and procedures and ration contrast supplies. Photo by Dave Fornell

How to manage patients in need of contrast-enhanced imaging following an allergic-like reaction

Up to one-third or more of patients who experience moderate or severe allergic-like reactions to ICM must have their imaging protocols revised when subsequent exams involving contrast are requested.

GBCA dose drops significantly in breast MRI thanks to machine learning

The use of synthetic images could reduce the amount of gadolinium-based contrast agents needed for breast MRI examinations, according to new data published this week in Radiology.

GE HealthCare's new MRI contrast agent advances to clinical trial

Experts are hopeful that the first-of-its-kind injectable manganese-based macrocyclic agent will offer a suitable alternative to GBCAs, as it can be more efficiently eliminated from the body.

Expert left 'astounded' by gadolinium discovery

New data out of the University of New Mexico suggest that the imaging agent’s physiologic reach may exceed what was previously believed.

Imaging Contrast

Low dose GBCA effective, safe for pediatric imaging

Bayer seeks FDA approval for gadoquatrane, its latest low-dose GBCA

FDA approves expanded use of 'powerful' lung imaging tool

Cardiac ultrasound contrast completely safe, despite reports to the contrary

FDA approves popular ultrasound enhancing agent for pediatric patients