Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography, RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

Tips for preventing 'unpredictable' hypersensitivity contrast reactions
Experts recently developed a new set of recommendations to help providers better navigate decisions related to contrast administration, sharing their guidance in Insights into Imaging.
Carbon dioxide a safe, effective contrast alternative for vascular procedures
Researchers believe that it could be especially beneficial in patients with impaired kidney function who may be at risk of adverse reactions to standard ICM.
Contaminated CT contrast blamed for 8 patient hospitalizations
After several radiology patients were sickened following an injection of iodinated contrast, the hospital where the incidents occurred has revealed the culprit.
Lowest dose gadolinium-based contrast agent to date inches closer to FDA approval
Gadoquatrane is now set to go through the regulatory review process on its trek to earning full FDA approval.
Woman dies following severe allergic reaction to CT contrast
The 22-year-old patient was undergoing a computed tomography exam with contrast due to her history of kidney stones.

Iodine contrast being loaded into a contrast injector in preparation for a cardiac CT scan at Duly Health and Care in Lisle, Illinois. The contrast shortage is causing some healthcare organizations to postpone exams and procedures and ration contrast supplies. Photo by Dave Fornell

Tips for preventing 'unpredictable' hypersensitivity contrast reactions

Experts recently developed a new set of recommendations to help providers better navigate decisions related to contrast administration, sharing their guidance in Insights into Imaging.

Carbon dioxide a safe, effective contrast alternative for vascular procedures

Researchers believe that it could be especially beneficial in patients with impaired kidney function who may be at risk of adverse reactions to standard ICM.

Contaminated CT contrast blamed for 8 patient hospitalizations

After several radiology patients were sickened following an injection of iodinated contrast, the hospital where the incidents occurred has revealed the culprit.

Lowest dose gadolinium-based contrast agent to date inches closer to FDA approval

Gadoquatrane is now set to go through the regulatory review process on its trek to earning full FDA approval.

Woman dies following severe allergic reaction to CT contrast

The 22-year-old patient was undergoing a computed tomography exam with contrast due to her history of kidney stones.

Fluorescent contrast agent helps diagnose basal cell carcinoma.

Fluorescent contrast agent noninvasively identifies common skin cancer

When used topically, the agent penetrates the skin and generates a fluorescent signal under the guidance of a fluorescent confocal microscope.

Bacteria-based contrast agent lights up tumor margins significantly better than other agents.

Bacteria-based contrast agent offers 'substantial improvements' for tumor border delineation during surgery

Essentially, the agent places a bright neon sign on the entirety of tumors and their borders, and it does so autonomously.

Low dose GBCA effective, safe for pediatric imaging

Although gadopiclenol is approved for adults and children ages 2 and older, there is limited data on its use in the pediatric population.