Pharmaceutics

This page contains key pharmaceutical news on drug recalls, FDA clearance, safety communications and research. In cardiology, key pharmaceutic agents include antiplatelet therapies, anticoagulants, hypertension drugs, and drugs for heart failure and arrhythmias.   

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Screening and treatment for chronic kidney disease in heart disease patients needs to be expanded

The risk associated with under-recognized CKD emerged early, highlighting the need for screening soon after a CAD diagnosis so that cardio-renal protective drugs can be started much earlier.

prescription drugs

Cost-related medication non-adherence declined after the Inflation Reduction Act

Lower Medicare drug costs translated into more patients taking their medications, leading to better outcomes.

Former American College of Cardiology president Hadley Wilson, MD, FACC, executive vice chair of Atrium Health's Sanger Heart and Vascular Institute, shared his thoughts on what he saw as the key studies in the above video interview with Cardiovascular Business. He covered numerous trials in more detail in the video. #ACC26 #ACC

Key clinical takeaways from ACC.26

Hadley Wilson, MD, a former American College of Cardiology president, spoke to Cardiovascular Business about several studies presented at ACC.26.

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Aggressively treating blood pressure, cholesterol levels fails to improve cognitive function

Targeting key cardiovascular risk factors for two full years was not linked to a reduced risk of cognitive decline or dementia.

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Early use of tirzepatide after heart attack or stroke linked to key cardiovascular benefits

When patients without diabetes land in the hospital after a heart attack or stroke, early treatment with tirzepatide may prove beneficial. 

overweight patient seeking health advice

Another win for Wegovy: FDA approves higher semaglutide dose as part of new pilot program

Novo Nordisk will be selling the new 7.2-mg dose under the brand name Wegovy HD. The FDA's decision fell under a new pilot program intended to grant certain companies improved access and quicker approvals. 

MiniMed Flex Medtronic

FDA clears MiniMed’s screenless, smartphone-controlled insulin pump

Just weeks after separating from Medtronic and going public, MiniMed secured FDA clearance for its next-generation insulin pump technology. 

A single injection of saNppa lipid nanoparticles enables self-amplification and high-yield pro-ANP production for more than 28 days. Circulating pro-ANP is selectively cleaved by the cardiac protease corin into active ANP, activating NPR1/cGMP signaling in the heart. Image courtesy of Science, Kaiyue Zhang et al. https://www.science.org/doi/10.1126/science.adu9394

Single injection could help heal heart attack damage

Amplifying the body’s natural release of a specific hormone may reduce stress on the heart and limit long‑term damage after myocardial infarctions.  

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