Pharmaceutics

This page contains key pharmaceutical news on drug recalls, FDA clearance, safety communications and research. In cardiology, key pharmaceutic agents include antiplatelet therapies, anticoagulants, hypertension drugs, and drugs for heart failure and arrhythmias.   

AMA brainstorms on key topics impacting healthcare

"With significantly strengthened penalties, standardized reporting requirements and unprecedented enforcement commitments, the regulatory landscape has dramatically shifted," the AMA wrote. 

heart drugs with stethoscope

How anticoagulants may impact a patient’s risk of gastrointestinal bleeding after TAVR

Researchers tracked the rates of major gastrointestinal bleeding in patients with AFib randomized to receive edoxaban or a vitamin K antagonist after a successful TAVR procedure.

COVID-19 vaccine vaccination myocarditis heart damage inflammation RSNA imaging radiology cardiology

FDA wants new heart damage warnings added to COVID-19 vaccines

COVID-19 vaccines are associated with a very low risk of myocarditis and/or pericarditis, primarily in young adults. The long-term impact of this risk has been the subject of many studies and debates over the years. One side says that the benefits of vaccination far outweigh the risks, and the other side says that even the smallest risk of heart damage is too high.

heart drugs with stethoscope

Work begins on first ATTR-CM study of its kind

ACT-EARLY is testing the hypothesis that treating asymptomatic carriers of a pathogenic TTR variant with the drug acoramidis could delay amyloidosis from developing.

Semaglutide works fast, protecting the heart before weight loss kicks in

"These results highlight semaglutide’s early action on decreasing major cardiovascular events," one cardiologist explained.

Many attendees shot selfies in front of the the massive heart on display in the Cytokinetic booth at AHA 2022.

New drug for obstructive HCM outperforms the current standard of care

Cytokinetics announced positive results from a new clinical trial comparing aficamten monotherapy to the beta blocker metoprolol.

Obicetrapib linked to substantial reductions in LDL cholesterol for high-risk heart patients

Researchers shared new studies on the highly selective CETP inhibitor in The New England Journal of Medicine and The Lancet.

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High Lp(a) levels increase risk of repeat cardiovascular events—LDL drugs may help

Researchers evaluated data from more than 273,000 patients with a history of ASCVD, noting that higher Lp(a) levels are consistently linked to worse cardiovascular outcomes.