Pharmaceutics

This page contains key pharmaceutical news on drug recalls, FDA clearance, safety communications and research. In cardiology, key pharmaceutic agents include antiplatelet therapies, anticoagulants, hypertension drugs, and drugs for heart failure and arrhythmias.   

doctor patient elderly check up hospital

FDA approves labeling changes for fenofibrates due to lack of cardiovascular benefits

The FDA listened to physician feedback and updated its labeling requirements for fenofibrates. These drugs have not been linked to any significant cardiovascular benefits, and clinicians should act accordingly.

Lasix ONYU

FDA approves subcutaneous diuretic treatment for heart failure-related edema

The newly approved drug-device combination helps patients manage their own treatment from the comfort of home. 

obesity semaglutide tirzepatide GLP-1 drugs weight loss

Obesity drugs under review: Semaglutide, tirzepatide, naltrexone/bupropion all boost heart health

The popularity of various obesity management medications has increased significantly in recent years. According to a new analysis of more than 60,000 patients, some of these drugs are associated with more cardiovascular benefits than others.

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DAPT during valve-in-valve TAVR may reduce stroke risk—more data still required

New research suggests there may be a cardiovascular benefit to considering dual antiplatelet therapy for valve-in-valve TAVR patients.

The universal screening of children for familial hypercholesterolemia can save lives

If familial hypercholesterolemia is not detected and treated early, it can lead to premature heart attacks and heart disease in young patients.

A new ACC consensus document of coronary inflammation calls for wider use of hs-CRP testing to identify more patients with residual heart attack risk, even if they are optimal statin therapy.

ACC calls for more screening in new scientific statement on inflammation

The document provides an in-depth look at the close relationship between inflammation and cardiovascular disease. "The time for taking action has now arrived," the authors wrote. 

Vulnerable, but treatable: Semaglutide reduces symptoms in high-risk heart failure patients

Yes, even frail HFpEF patients see significant benefits when treated with semaglutide. Researchers believe these new data may help ease the minds of cardiologists everywhere.

Evinacumab-dgnb is sold by Regeneron under the brand name Evkeeza

FDA approves treatment of rare genetic disorder in children as young as 1 year old

Evinacumab-dgnb, sold by Regeneron under the brand name Evkeeza, can now be used to treat homozygous familial hypercholesterolemia in much younger patients.