Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Heart failure symptoms after PCI increase risk of adverse events

Researchers in Japan tracked BNP levels and bleeding events among more than 7,000 PCI patients. The group noted that managing heart failure in the first 30 days after PCI can help boost outcomes. 

FDA approves Abbott’s Aveir dual chamber (DR) leadless pacemaker system, the world’s very first dual chamber leadless pacing solution for treating patients with abnormal heart rhythms.

FDA approves world’s first dual-chamber leadless pacemaker system

The minimally invasive system is made up of two pacemakers that send signals back and forth to one another. One pacemaker is placed on the patient's right ventricle, and the other is placed on the patient's right atrium. 

TricValve Transcatheter Bicaval Valves System and HeartMate II LVAD

Cardiologists shed new light on treating severe tricuspid regurgitation in high-risk heart failure patients

The 80-year-old patient was experiencing severe TR and already had a HeartMate II LVAD. 

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‘A hugely significant development’: Severe heart condition reverses in 3 patients, shocking experts

Cardiologists and other physicians have always believed cardiac transthyretin amyloidosis, a progressive heart condition associated with a high mortality rate, was irreversible. Now, though, new evidence suggests that there may be hope. 

FDA warns healthcare providers about recalled CPB, ECMO devices

Multiple medical devices used during cardiopulmonary bypass and extracorporeal membrane oxygenation procedures have been voluntarily recalled due to issues with their packaging.

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FDA announces recall of certain Impella heart pumps after 3 patient injuries, nearly 200 complaints

The FDA has labeled this as a Class I recall, which means using these devices can lead to significant injuries, including death.

Jagmeet Singh, MD, explains details of the SOLVE-CRT pivotal clinical trial at HRS 2023. #HRS #HRS2023

VIDEO: Jagmeet Singh details the SOLVE-CRT study for a leadless CRT system

Findings from the SOLVE-CRT study were presented to attendees at Heart Rhythm 2023. "Our results showed the study was safe, effective and feasible," Singh said. 

FDA approves sotagliflozin, the new heart failure drug from Lexicon Pharmaceuticals

The drug, which should be available by the end of June, will be marketed under the name Inpefa.