Heart Failure

Heart failure occurs when the heart cannot pump as much blood as the body requires. This ineffective pumping can lead to enlargement of the heart as the myocardium works harder pump the same amount of blood. Heart failure may be caused by defects in the myocardium, such as an a heart attack infarct, or due to structural issues such as severe heart valve regurgitation. Heart failure can be divided into HF with preserved ejection fraction (HFpEF), and HF with reduced ejection fraction (HFrEF). The disease is further divided into four New York Heart Association (NYHA) classes. Stage IV heart failure is when the heart is completely failing and requires a heart transplant or hemodynamic support from a left ventricular assist device (LVAD).

Dapagliflozin improves outcomes for elderly TAVR patients with heart failure
The positive data were presented as part of a late-breaking clinical trial at ACC.25 in Chicago. One cardiologist on stage for the presentation said these findings will impact the way he manages certain TAVR patients.
FDA approves vutrisiran to treat ATTR-CM
The subcutaneous drug, sold under the brand name Amvuttra, joins an ATTR-CM market that already includes Pfizer’s tafamidis (Vyndaqel, Vyndamax) and BridgeBio’s acoramidis (Attruby).
Direct marketing to cardiologists increases uptake of some, but not all, heart failure drugs
Researchers tracked three years of CMS data to explore how meal-based marketing may influence the habits of general and advanced heart failure cardiologists.
Cannabis use increases risk of heart attack, stroke in young adults
“Asking about cannabis use should be part of clinicians' workup to understand patients' overall cardiovascular risk, similar to asking about smoking cigarettes,” one researcher said. Additional details will be presented at ACC.25 in Chicago.
Patient discharged with total artificial heart for first time—goes 105 days while awaiting transplant
Total artificial heart recipients typically stay in the hospital. In this case, however, the patient was able to wait for a donated heart from the comfort of his own home.

Death after TAVR: Heart failure, sudden cardiac arrest stand out as 2 leading causes

A majority of patient deaths within two years of TAVR can be linked to cardiovascular complications, according to new research published in JACC: Cardiovascular Interventions. Can follow-up care be improved to combat this trend?

Overlapping concerns: 5 takeaways from a new study on CVD, CKD and type 2 diabetes among US adults

How common is it for patients to present with overlapping cardiac, renal and metabolic issues? A new analysis in JAMA Cardiology explored that very question.

Surgeons with University of Maryland Medical Center transplant a pig heart into a human patient

Surgeons make history again, transplant pig heart into human patient for second time ever

That same team that transplanted a pig heart into a human patient for the very first time in 2022 has now done it again. The patient is currently recovering from the procedure, which occurred on Sept. 20.

FDA approves empagliflozin for treating chronic kidney disease

The popular SGLT2 inhibitor, sold by Boehringer Ingelheim and Eli Lilly and Company under the name Jardiance, has already been approved by the FDA to treat type 2 diabetes and heart failure.

K-Clip Transvascular Tricuspid Repair System from Huihe Healthcare

Cardiologists use new annular clipping device for first time in US to treat severe tricuspid regurgitation

Interventional cardiologists with Henry Ford Health performed the historic procedure on an 85-year-old patient who had been experiencing worsening symptoms for a full year.

Low-cost generic programs offer CVD medications at affordable prices—but availability changes from one to the next

Programs managed by H-E-B, Kroger, Mark Cuban Cost Plus Drug Company and Walmart appear to offer the most options for CVD patients. When it comes to AFib and heart failure, however, researchers believe the choices could be improved.

Arzhang Fallahi, MD, and David Hsi, MD, discussing imaging-based aortic stenosis screening

Q&A: Cardiologists explore the potential impact of a screening program for aortic stenosis

We already screen patients for breast cancer and lung cancer on a regular basis. Why not establish screening programs for aortic stenosis?

Purvi Parwani, MD, director of echocardiography, Loma Linda University Medical Center, explains the trend where heart failure imaging guidelines are driving a rising use of mixed multimodality imaging. #ASE #ASE2023

Multimodality imaging helps cardiologists manage heart failure patients—with an assist from AI

Purvi Parwani, MD, discussed the trend toward multimodality imaging for heart failure management. All modalities have their own weaknesses, she explained.

Heart Failure

Dapagliflozin improves outcomes for elderly TAVR patients with heart failure

FDA approves vutrisiran to treat ATTR-CM

Direct marketing to cardiologists increases uptake of some, but not all, heart failure drugs

Cannabis use increases risk of heart attack, stroke in young adults

Patient discharged with total artificial heart for first time—goes 105 days while awaiting transplant