Clinical Research

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Opioid overdose medications may be more effective in women, according to new PET imaging study

Experts involved in a new analysis suggest their findings could help bring about more effective treatments for opioid use disorders. 

Joshua Joseph, MD, MPH, FAHA an expert in Cardiovascular-Kidney-Metabolic (CKM) syndrome, associate professor of internal medicine, and the Endowed Professor for Research in Internal Medicine in the Division of Endocrinology, Diabetes and Metabolism at The Ohio State University Wexner Medical Center, explains the CKM advisory from the American Heart Association designed to help define and stage the disease. CKM has seen a large amount of growing interest from cardiologists in recent years.

Interest rising in CKM syndrome as connections become clearer

Cardiovascular-kidney-metabolic (CKM) syndrome is a popular research topic among cardiologists, highlighting just how closely obesity, type 2 diabetes, chronic kidney disease and cardiovascular disease are related to one another. Joshua Joseph, MD, spoke to Cardiovascular Business about this ongoing trend.

The use of intravascular lithotripsy (IVL) during percutaneous coronary intervention (PCI) is still safe and effective when patients present with calcified nodules (CNs), according to new long-term data published in EuroIntervention.[1] Researchers compared outcomes from patients with and without CNs, highlighting key similarities in stent expansion and luminal gain.

Complications after intravascular lithotripsy are rare, real-world data confirm

Shockwave Medical, now a part of Johnson & Johnson MedTech, has consistently been found safe for patients. However, many previous clinical trials excluded high-risk patients, making it important to track real-world outcomes as time goes on.

Acupuncture improves brain structure in TBI patients

MR imaging shows how acupuncture improves brain structure after TBI

New research suggests acupuncture therapy can improve white matter integrity and help reduce the symptoms associated with severe concussions.

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PET imaging findings support use of intranasal drug delivery for Alzheimer's patients

The discovery is giving researchers vital new information that can be used to develop precision treatments for neurological conditions. 

Bacteria-based contrast agent lights up tumor margins significantly better than other agents.

Bacteria-based contrast agent offers 'substantial improvements' for tumor border delineation during surgery

Essentially, the agent places a bright neon sign on the entirety of tumors and their borders, and it does so autonomously. 

Toby Rogers, MD, Medstar, discusses a new dedicated device for BASILICA used in TAVR.

New device could make it easier than ever for cardiologists to perform BASILICA before TAVR

Toby Rogers, MD, PhD, noted that BASILICA is a fairly complex procedure. Using this advanced technology, however, could make it easier to perform and improve patient access.

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How sample sizes versus scan times affect data quality and radiology research overhead costs

New findings have the potential to significantly benefit the field of neuroscience and could help guide researchers in designing more cost-effective, fruitful studies of the brain.