Clinical Research

First US patient enrolled in device study to reduce coronary microvascular dysfunction
The self-expanding A-Flux device is implanted in the coronary sinus to increase pressure on the venous side of the heart and improve perfusion in smaller vessels.
Advances in leadless conduction and Bachmann’s bundle pacing next frontier in physiologic pacing
Leadless pacing in the Bachmann's bundle may be the next phase in the evolution of cardiac pacing technology.
Vibrations used to extract EP leads in first-in-human study
A novel vibration-based extraction technique appears to offer safety, efficiency and a simple, rapid, alternative to conventional lead removal.
AFib patients with gout face greater stroke risk—but therapy can help
Gout often goes undertreated, but targeting these patients with urate-lowering therapy can make a big impact on their long-term cardiovascular health.
Boston researchers land $9M grant to advance molecular neuroimaging
Researchers in Boston are set to co-lead a long-term study on the aging brain and factors that make individuals more vulnerable to neural injury and cognitive decline.

Premature menopause linked to substantial long-term heart risks

Starting menopause before the age of 40 could increase a woman's lifetime risk of coronary heart disease by up to 40%.

Cold weather responsible for many more stroke and heart attack deaths than heat

While heat consistently gets more attention in terms of public health messaging, new data show just how dangerous the cold can be.

'Leaky' blood brain barrier causes long-term damage years after head injuries

MRI findings detail how a 'leaky' barrier can damage the brain years after head injuries

New evidence suggests the BBB can remain compromised following a head injury, even years after it first occurred.

A single injection of saNppa lipid nanoparticles enables self-amplification and high-yield pro-ANP production for more than 28 days. Circulating pro-ANP is selectively cleaved by the cardiac protease corin into active ANP, activating NPR1/cGMP signaling in the heart. Image courtesy of Science, Kaiyue Zhang et al. https://www.science.org/doi/10.1126/science.adu9394

Single injection could help heal heart attack damage

Amplifying the body’s natural release of a specific hormone may reduce stress on the heart and limit long‑term damage after myocardial infarctions.

Researchers develop program that can spot falsified radiology reports written by AI

“With generative AI becoming more capable of producing remarkably convincing radiology reports, there’s a greater risk of fabricated reports being used to falsify medical histories and support fraudulent claims,” the team cautioned.

Several interventional cardiology late-breaking studies were presented at the Cardiovascular Research Technologies (CRT) 2026 meeting March 7-10, and experts from the Society of Society highlighted what they felt was most impactful to clinical practice. Photo by Dave Fornell.

CRT 2026: Key takeaways for interventional cardiologists

CRT studies shed new light on many topics, including long-term TAVR outcomes, radiation protection and advanced interventional techniques.

High costs may be keeping working-age heart patients from seeking care

When working-age adults develop cardiovascular disease, it often ends up eating up a significant amount of their income. Are insurance companies doing enough to help these patients?

Angiography demonstrates a high-grade, modestly angulated stenosis (arrow) in the proximal segment of a large diagonal branch (A). Predilation performed with difficulty, and the GEC could not be advanced beyond stenosis even with “inch worming” techniques. (B). Advancement of the CrossFAST (C) beyond the proximal stent edge stenosis (a.), the position of the distal end of the outer catheter (b.), and the microcatheter tip (c.) are indicated.

Next-generation guide extension catheter delivers value during complex PCI

The CrossFAST system was successfully used to deploy multiple stents after other devices fell short.

Clinical Research

First US patient enrolled in device study to reduce coronary microvascular dysfunction

Advances in leadless conduction and Bachmann’s bundle pacing next frontier in physiologic pacing

Vibrations used to extract EP leads in first-in-human study

AFib patients with gout face greater stroke risk—but therapy can help

Boston researchers land $9M grant to advance molecular neuroimaging