Clinical Research

S. Chris Malaisrie, MD, professor of surgery at Northwestern University Feinberg School of Medicine, and attending cardiac surgeon at the Bluhm Cardiovascular Institute of Northwestern Medicine, explains the late-breaking TAVR for failing bioprosthetic surgical valves five year outcomes from the PARTNER 3 Aortic Valve-in-Valve Registry at CRT 2025.

TAVR for failing surgical valves: Lessons learned from new 5-year data

S. Chris Malaisrie, MD, professor of surgery at Northwestern University, explained what these data can tell us about the lifetime management of patients who require aortic valve replacement.

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Prostate cancer radiotherapy timeline can be safely shortened

Isodose moderately hypofractionated radiotherapy allows patients to undergo just 4-5 weeks of treatment, compared to conventional therapy that can take around 8. 

Researchers track dopamine receptors to study its impact on cognitive function.

New PET study offers insight into how dopamine drives executive function

These findings could help guide the development of new treatments for psychiatric and neurological disorders.  

Howard Herrmann, MD, University of Pennsylvania, explains details of the SMART Trial 2-year results at CRT 2025, where Evolut performed better hemodynamically than the Sapien 3 TAVR valve in small annuli patients. The study included 87% women.

SMART 2-year TAVR hemodynamic data: Medtronic Evolut is better compared to Edwards Sapien in small annulus patients

Sponsored by Medtronic

Howard Herrmann, MD,  MSCAI, Hospital of the University of Pennsylvania, and lead invesigator for the SMART trial, explains details on the 2-year data comparing the Evolut vs. Sapien 3 for TAVR in small annulus patients.

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Sports-related concussion damage may persist long after return to play, study finds

Researchers in Toronto used MRI scans to measure the brain as it heals after injury. They found damage persists for a year after athletes are medically cleared to return to the field. 

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3D imaging reveals details of cranial bone aging

A group of researchers used 3D imaging to examine changes in the skulls of mice as they age, revealing a new perspective on how older bones heal.

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Report: NIH continues to pull research grants, in violation of court orders

While the policy of President Donald Trump is to axe research on transgender issues and DEI, scientists who spoke to the Boston Globe said their work does not run up against those restrictions. 

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New radiopharmaceutical targeted at gastrointenstinal cancers yields impressive results

Trial results thus far indicate the drug can significantly extend progression-free survival compared to current standard of care treatments.