Acute Coronary Syndromes

Acute coronary syndrome (ACS) is most commonly caused by a heart attack (myocardial infarction) where blood flow to the heart is suddenly blocked. This is usually caused by a blood clot from a ruptured coronary artery atherosclerotic plaque. Other causes include spontaneous coronary artery dissection (SCAD), which most commonly occurs in women. ACS is usually treated in a cath lab with angioplasty and the placement of a stent to prop the vessel open.

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Framingham Heart Study lands $38M grant for 6 more years of research

The 71-year-old Framingham Heart Study has received $38 million from the National Heart, Lung, and Blood Institute to fund a new six-year study into the biology of aging.

Ticagrelor reversal agent receives FDA breakthrough therapy designation

The FDA has granted a breakthrough therapy designation to a novel reversal agent for ticagrelor called PB2452, PhaseBio Pharmaceuticals announced April 8.

The risks, benefits of polypharmacy after MI for frail nursing home residents

Nursing home residents who were prescribed three or four preventive medications after myocardial infarction (MI) were 26% less likely to die within 90 days than those prescribed only one drug, researchers reported April 9 in Circulation: Cardiovascular Quality and Outcomes.

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AI-based vocal analysis could detect CAD, other conditions

The promise of artificial intelligence to revolutionize healthcare is the topic of increasing research, with new publications every day devoted to the topic. One of these applications, according to an April 1 article in The Wall Street Journal, is using AI to listen to a person’s voice and detect a range of mental and physical ailments, including coronary artery disease (CAD).

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Primary prevention guideline downgrades aspirin, highlights social determinants

NEW ORLEANS — Described by its authors as “a one-stop shop” for the primary prevention of cardiovascular disease, a new guideline released March 17 by the American Heart Association (AHA) and the American College of Cardiology (ACC) runs the gamut from smoking cessation strategies to specific recommendations for treating cholesterol based on a patient’s 10-year risk of atherosclerotic cardiovascular disease.

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Switch to daylight saving time linked to spike in heart attacks

As people around the country struggle to catch up on sleep after “springing forward” an hour, a Washington Post story reminds us of the health risks associated with adjusting our clocks, including an increased incidence of heart attacks.

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Longitudinal C-reactive protein elevations linked to adverse outcomes after ACS

Both initial and serial increases in high-sensitivity C-reactive protein (hsCRP) concentrations are independently predictive of cardiac events following acute coronary syndrome (ACS), according to a new study in JAMA Cardiology.

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Heart attacks growing more common among people in their 20s and 30s

The proportion of heart attack patients who are 40 or younger has steadily increased over the last decade, according to research set to be presented March 17 at the American College of Cardiology’s scientific sessions in New Orleans.