Acute Coronary Syndromes

Acute coronary syndrome (ACS) is most commonly caused by a heart attack (myocardial infarction) where blood flow to the heart is suddenly blocked. This is usually caused by a blood clot from a ruptured coronary artery atherosclerotic plaque. Other causes include spontaneous coronary artery dissection (SCAD), which most commonly occurs in women. ACS is usually treated in a cath lab with angioplasty and the placement of a stent to prop the vessel open.

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PCSK9 inhibitors might protect AMI survivors against reperfusion-related brain damage

Research published in the Journal of the American Heart Association Jan. 13 has concluded administering PCSK9 inhibitors to acute MI patients ahead of ischemia can mitigate the potential negative neurological effects that come with treatment.

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Vaspin shows promise for predicting MACE in patients with AMI

Measuring blood levels of vaspin could independently predict major adverse cardiac events (MACE) in patients who have suffered acute myocardial infarction (AMI), according to research published Jan. 16 in the Journal of the American Heart Association, potentially improving early risk stratification in heart attack survivors.

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Sleeping less than 6 hours a night could raise risk for atherosclerosis

Sleeping less than six hours a night or experiencing poor-quality rest has been independently linked to an increased risk of subclinical multiterritory atherosclerosis, a team of Spanish researchers reported in the Journal of the American College of Cardiology Jan. 14.

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Any amount of physical activity could cut risk of early death

A study published online in the American Journal of Epidemiology Jan. 14 suggests any physical movement, whether it’s short, long, intense or mild, counteracts the negative cardiovascular effects of sitting for long periods.

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High troponin without MI still dangerous in long run

Elevated levels of cardiac troponin signal an increased risk of cardiovascular events even when the cause of that elevation is unknown, suggests a study published in the Journal of the American College of Cardiology.

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Statin adherence remains low in post-MI, high-risk patients

A study published Jan. 8 in the Journal of the American Heart Association suggests patient adherence to statin therapy in the U.S. remains low, particularly among younger individuals, minorities and those recommended for high-intensity regimens.

Nicardipine reverses overlooked cause of chest pain

The calcium-channel blocker nicardipine can effectively reverse coronary slow flow (CSF)—“an under-recognized cause of chest pain”—according to the authors of a study published online Dec. 15 in the Journal of Invasive Cardiology.

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High financial burden drives depression, poor quality of life in ASCVD patients

Patients with atherosclerotic cardiovascular disease (ASCVD) who struggle to pay their medical bills are at a higher risk for psychological distress, depression and a poor quality of life, according to research published in Circulation: Cardiovascular Quality and Outcomes.