Acute Coronary Syndromes

Acute coronary syndrome (ACS) is most commonly caused by a heart attack (myocardial infarction) where blood flow to the heart is suddenly blocked. This is usually caused by a blood clot from a ruptured coronary artery atherosclerotic plaque. Other causes include spontaneous coronary artery dissection (SCAD), which most commonly occurs in women. ACS is usually treated in a cath lab with angioplasty and the placement of a stent to prop the vessel open.

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Alirocumab reduces risk of initial and repeat CV events after ACS

An extended analysis of the ODYSSEY OUTCOMES trial has confirmed alirocumab, a PCSK9 inhibitor that hit the medical market in 2015, reduces a patient’s total risk of nonfatal and fatal cardiovascular events after an acute coronary syndrome (ACS).

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Archaeologists find evidence heart disease was alive and well in the 1500s

Archeologists have uncovered evidence of atherosclerosis in a handful of 500-year-old mummies from Greenland, Forbes reported.

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Troponin elevations in ‘normal range’ predict near-term cardiac events

Higher concentrations of troponin—even those that were within a “normal range”—signal increased odds of adverse outcomes among outpatients with stable chest pain, suggesting the biomarker test may improve risk stratification and inform management strategies for this common clinical scenario.

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PCSK9 inhibitors might protect AMI survivors against reperfusion-related brain damage

Research published in the Journal of the American Heart Association Jan. 13 has concluded administering PCSK9 inhibitors to acute MI patients ahead of ischemia can mitigate the potential negative neurological effects that come with treatment.

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Vaspin shows promise for predicting MACE in patients with AMI

Measuring blood levels of vaspin could independently predict major adverse cardiac events (MACE) in patients who have suffered acute myocardial infarction (AMI), according to research published Jan. 16 in the Journal of the American Heart Association, potentially improving early risk stratification in heart attack survivors.

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Sleeping less than 6 hours a night could raise risk for atherosclerosis

Sleeping less than six hours a night or experiencing poor-quality rest has been independently linked to an increased risk of subclinical multiterritory atherosclerosis, a team of Spanish researchers reported in the Journal of the American College of Cardiology Jan. 14.

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Any amount of physical activity could cut risk of early death

A study published online in the American Journal of Epidemiology Jan. 14 suggests any physical movement, whether it’s short, long, intense or mild, counteracts the negative cardiovascular effects of sitting for long periods.

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High troponin without MI still dangerous in long run

Elevated levels of cardiac troponin signal an increased risk of cardiovascular events even when the cause of that elevation is unknown, suggests a study published in the Journal of the American College of Cardiology.