Gene editing process leads to personalized advice for heart patient

University of Pennsylvania researchers have developed a stem cell-based test to determine whether genetic variants in heart muscle cells are benign or pathogenic. In other words, they’ve added some certainty to variants of uncertain significance—the tricky alleles that can either contribute to the development of diseases or be completely harmless.

Study: SAVR mortality predicts TAVR outcomes in US hospitals

Hospitals with favorable outcomes for surgical aortic valve replacement (SAVR) procedures subsequently see better transcatheter aortic valve replacement (TAVR) outcomes when they launch TAVR programs, researchers reported in JAMA Cardiology Dec. 5, suggesting the quality of an institution’s surgical team could be an indicator of how they’ll fare after they initiate TAVR.