Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

Example of spectral, or dual-energy CT, confirming a pulmonary embolism (PE). Image courtesy of Philips Healthcare

MRA vs CTA for evaluating pulmonary embolism: Does the chosen modality impact downstream imaging utilization?

MR angiography (MRA) is a relatively new alternative to CT angiography (CTA) for the evaluation of suspected pulmonary embolism (PE) and it even has one major advantage over CTA: it does not expose patients to ionizing radiation.

Meta-analysis: Intensive lipid lowering only beneficial at higher LDL levels

Intensive lipid-lowering therapy significantly reduces all-cause and cardiovascular mortality—but only for patients with low-density lipoprotein cholesterol (LDL-C) levels above 100 mg/dL, according to a meta-analysis published April 17 in JAMA.

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Slower nighttime transfers of stroke patients may reduce odds of thrombectomy

Transfer times to an endovascular therapy-capable hospital are an average of 20 minutes slower during nighttime hours at one hub-and-spoke stroke network, possibly leading to a lower likelihood of those patients receiving thrombectomy.

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Women underrepresented in clinical trials for heart failure, acute coronary syndrome

While women are equally or overrepresented in clinical trials for hypertension, atrial fibrillation (AFib) and pulmonary arterial hypertension, they are underrepresented in clinical trials for heart failure, coronary artery disease and acute coronary syndrome, according to a new study published in the Journal of the American College of Cardiology.

Eidos Therapeutics Initiates Phase 2 Clinical Trial for AG10 Targeting Transthyretin Amyloidosis Cardiomyopathy

SAN FRANCISCO, May 3, 2018 /PRNewswire/ — Eidos Therapeutics, Inc., a clinical stage biopharmaceutical company developing a novel oral therapy to treat transthyretin (TTR) amyloidosis (ATTR), today announced dosing of the first patient in the Phase 2 clinical trial of AG10 in patients with ATTR cardiomyopathy.

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Abbott’s XIENCE Sierra stent to be reimbursed through insurance in Japan

Abbott’s XIENCE Sierra, the newest generation of the company’s everolimus-eluting coronary stent, has been approved for national reimbursement in Japan.

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AHA/ASA retracts large portion of new stroke guidelines

The American Heart Association (AHA)/American Stroke Association (ASA) is revisiting its recently updated stroke guidelines after issuing a “correction” that removed several portions.

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Bystander CPR, defibrillation only helpful for finite period

A new nationwide study from Japan highlighted the importance of timely ambulance arrival, showing that bystander defibrillation and cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest are essentially worthless if EMS response times are slower than 13 minutes and 11 minutes, respectively.