Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

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TCT.18: BIONYX finds novel zotarolimus-eluting stent noninferior to Orsiro

Resolute Onyx, a polymer-coated zotarolimus-eluting stent, has been proven safe and effective in an all-comer population of more than 2,000 heart patients, according to late-breaking results of the BIONYX trial.

TCT.18: TAVR outcomes not swayed by valve type, anesthesia approach

SAN DIEGO — General and local anesthesia are comparably safe and effective during transcatheter aortic valve replacement (TAVR) procedures, according to the first randomized trial to compare the two approaches.

TCT.18: COAPT draws superlatives, raises questions about replicating MitraClip’s benefits

Compared to heart failure patients with severe secondary mitral regurgitation who were treated with guideline-directed medical therapy alone, those randomized to a MitraClip procedure plus optimal medical therapy demonstrated relative reductions of 47 percent for heart failure hospitalizations and 38 percent for mortality at two years of follow-up.

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TCT.18: Ultra-thin Orsiro stent outperforms Xience at 2 years of follow-up

SAN DIEGO — The ultra-thin Orsiro drug-eluting stent (DES) maintained superior outcomes at two years of follow-up in a head-to-head trial against Abbott’s Xience stent, according to results presented this weekend at Transcatheter Cardiovascular Therapeutics 2018 and published online in the Journal of the American College of Cardiology.

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OHCA protocol with angiography, therapeutic cooling slashes mortality rates

A strict protocol mandating coronary angiography and therapeutic hypothermia contributed to “startling” improvements in survival rates for out-of-hospital cardiac arrest (OHCA), researchers reported in JACC: Cardiovascular Interventions.

38% of AFib patients feel ‘trapped’ between risks of stroke, anticoagulants

Atrial fibrillation patients are acutely aware of their five-fold increased risk of stroke, new research from StopAfib.org suggests—and 38 percent report feeling “trapped” between their fear of having a stroke and the major bleeding risks associated with anticoagulants.

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Early compression therapy improves prognosis for deep vein thrombosis

Patients who suffer from deep vein thrombosis (DVT) see a “clear benefit” from initiating preventive compression therapy shortly after their diagnosis, as opposed to later stages of treatment, according to a study published this week in the journal Blood.

Is age ‘just a number' when it comes to PCI patients in their 90s?

The proportion of percutaneous coronary interventions (PCIs) performed in nonagenarians has more than doubled in the last decade in the United States, offering a significant survival benefit for those deemed healthy enough for the procedure, according to a study published online Sept. 17 in JACC: Cardiovascular Interventions.