Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

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TCT.18: ReCre8 finds polymer-free stent safe, effective for clinical use

A novel, polymer-free amphilius-eluting stent known as the “Cre8” was proven noninferior to the latest-generation permanent polymer drug-eluting stent in the first large-scale trial of its kind, according to research presented at the Cardiovascular Research Foundation’s 30th annual TCT conference in San Diego.

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TCT.18: Ultrasound-based renal denervation tops radiofrequency ablation for BP lowering

SAN DIEGO — An endovascular ultrasound-based renal denervation (RDN) approach led to greater reductions in blood pressure than radiofrequency ablation in patients with resistant hypertension, according to the first randomized trial to compare the techniques.

Obesity to overtake smoking as No. 1 cause of preventable cancers in women

A report published by charity organization Cancer Research U.K. suggests obesity is on track to eclipse smoking as the greatest cause of preventable cancer in British women—something experts say could happen by 2043, the Guardian has reported.

TCT.18: Anticipated OAC-ALONE results ‘underpowered, inconclusive’

OAC-ALONE, the first randomized trial to test the efficacy of oral anticoagulation (OAC) alone against combined OAC and a single antiplatelet agent (APT) in patients with atrial fibrillation and stable coronary artery disease, was unable to establish noninferiority of OACs to dual therapy, according to data presented at the 30th annual TCT conference in San Diego.

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Taller height identified as risk factor for development of varicose veins

Height—and the genes that influence it—are important predictors for the development of varicose veins, according to a study out of Stanford University.

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TCT.18: BIONYX finds novel zotarolimus-eluting stent noninferior to Orsiro

Resolute Onyx, a polymer-coated zotarolimus-eluting stent, has been proven safe and effective in an all-comer population of more than 2,000 heart patients, according to late-breaking results of the BIONYX trial.

TCT.18: TAVR outcomes not swayed by valve type, anesthesia approach

SAN DIEGO — General and local anesthesia are comparably safe and effective during transcatheter aortic valve replacement (TAVR) procedures, according to the first randomized trial to compare the two approaches.

TCT.18: COAPT draws superlatives, raises questions about replicating MitraClip’s benefits

Compared to heart failure patients with severe secondary mitral regurgitation who were treated with guideline-directed medical therapy alone, those randomized to a MitraClip procedure plus optimal medical therapy demonstrated relative reductions of 47 percent for heart failure hospitalizations and 38 percent for mortality at two years of follow-up.