Percutaneous coronary intervention (PCI) guided by fractional flow reserve (FFR) was associated with a 54 percent reduction in the composite endpoint of death, myocardial infarction and urgent revascularization when compared to medical therapy alone, according to five-year data from the FAME 2 trial.

New research from Florida State University suggests depression screening in patients with coronary artery disease (CAD) is especially crucial, because those individuals tend to have higher rates of morbidity and mortality.

Despite being performed in an older population with more cardiovascular comorbidities, transcatheter aortic valve replacement (TAVR) demonstrated similarly low rates of postoperative stroke and mortality compared with surgical aortic valve replacement (SAVR) in a study of patients with previous strokes.

Although survival after congenital heart surgery is improving, patients who receive procedures for even mild defects have long-term mortality rates at least three times higher than their counterparts in the general population, according to a U.S.-based registry study published in the Journal of the American College of Cardiology.

Patients who suffer minor ischemic stroke or a transient ischemic attack (TIA) can lower the risk for a major stroke within 90 days by taking both clopidogrel and aspirin, according to a study published online May 16 in The New England Journal of Medicine.

Children who experienced partial readmission of new-onset type 1 diabetes had significantly lower total cholesterol levels and LDL cholesterol levels compared with non-remitters four to five years after diagnosis, according to a single-center study published May 16 in PLOS One.

Saphenous vein graft (SVG) lesions can be treated just as well with bare metal stents (BMS) as drug-eluting stents (DES), suggests a double-blind, randomized trial published May 11 in The Lancet.

Researchers from the University of California Los Angeles (UCLA) have developed a new algorithm which better predicts pre- and post-heart transplant survival than existing methods.