Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

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FDA OKs Resolute stents for treatment of chronic total occlusion

Two of Medtronic’s drug-eluting stents (DES)—the Resolute Onyx and the Resolute Integrity—have been granted FDA approval to treat coronary artery disease patients with chronic total occlusion (CTO), the company announced Feb. 26.

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Women see worse outcomes after thoracic aortic surgery

Women see worse outcomes than men after thoracic aortic surgery requiring hypothermic circulatory arrest (HCA), researchers reported in the Feb. 26 edition of Circulation.

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When should stroke thrombectomy be considered futile?

When endovascular thrombectomy procedures for acute ischemic stroke take more than an hour or require more than three attempts to remove the clot, outcomes significantly worsen, according to a study published Feb. 25 in the Journal of the American College of Cardiology.

FDA: Higher doses of tofacitinib tied to increased risks of death, pulmonary embolism

The FDA issued a safety alert Feb. 25 warning that a 10 mg, twice-daily dose of tofacitinib—sold under the brand names Xeljanz and Xeljanz XR—has been linked to an increased risk of pulmonary embolism and death in patients with rheumatoid arthritis. That dose is only approved for patients with ulcerative colitis, the agency said.

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42% of HF patients take at least 10 meds a day—and they’re willing to add more

Nearly half of patients with heart failure (HF) take at least 10 medications per day, according to research published in the American Journal of Cardiology, yet an overwhelming 85 percent report willingness to add more drugs to that regimen if it helps them prevent further health events.

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Morning walks, sitting breaks counter high BP in older adults

A half-hour walk in the morning lowers blood pressure (BP) in overweight and obese men and women predisposed to heart disease, according to a study published in Hypertension Feb. 20.

2 years after study finds Celebrex heart-safe, research links drug to valve calcification

More than two years after a major New England Journal of Medicine study declared arthritis drug Celebrex safe for use in heart patients, new research published in JACC: Basic to Translational Science Feb. 22 suggests the drug might actually raise users’ risk for heart valve calcification.

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Ultra-thin Orsiro stent gains FDA approval

The ultra-thin Orsiro drug-eluting stent (DES) has received FDA approval and is now commercially available in the United States, device manufacturer Biotronik announced Feb. 22.