Experimental gene therapies to treat hemophilia are still undergoing testing, but early results from clinical trials have both researchers and patients optimistic the condition can be cured once and for all.

Maintaining an optimal body mass index (BMI), in addition to controlling other cardiovascular risk factors, may reduce the risk of peripheral artery disease (PAD) with critical limb ischemia (CLI), according to new research in the Journal of the American Heart Association.

The factor Xa inhibitor edoxaban might reduce the risk of several adverse events—including stroke, major bleeding and all-cause death—when compared to warfarin, according to a real-world study of Korean patients with atrial fibrillation (AFib).

Sodium intake is associated with cardiovascular disease (CVD) only in communities where the average intake is more than five grams per day, according to an update of the Prospective Urban Rural Epidemiology (PURE) study published in The Lancet.

Harvard scientist Sekar Kathiresan, MD, believes polygenic risk score could help identify people at high risk for heart attack. Kathiresan, director of the Cardiovascular Disease Initiative at the Broad Institute and a professor at Harvard Medical School, said polygenic risk scores, based on genetic testing, will be as commonly known as cholesterol levels. 

Estrogen may protect against heart failure (HF)-related depression by preventing the creation of inflammation-causing chemicals in the brain, according to research published in the American Journal of Physiology.

The FDA has approved migalastat, the first oral medication for the treatment of adults with Fabry disease, the agency announced Aug. 10.

A 45-year-old man who had a stroke now creates “eye-catching” pictures—a talent he didn’t have before the medical emergency. Wayne Sheppard of the United Kingdom now sells some of his paintings for up to $510 (or £400).