Clinical

This channel newsfeed includes clinical content on treating patients or the clinical implications in a variety of cardiac subspecialties and disease states. The channel includes news on cardiac surgery, interventional cardiologyheart failure, electrophysiologyhypertension, structural heart disease, use of pharmaceuticals, and COVID-19.   

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Gene editing process leads to personalized advice for heart patient

University of Pennsylvania researchers have developed a stem cell-based test to determine whether genetic variants in heart muscle cells are benign or pathogenic. In other words, they’ve added some certainty to variants of uncertain significance—the tricky alleles that can either contribute to the development of diseases or be completely harmless.

Study: SAVR mortality predicts TAVR outcomes in US hospitals

Hospitals with favorable outcomes for surgical aortic valve replacement (SAVR) procedures subsequently see better transcatheter aortic valve replacement (TAVR) outcomes when they launch TAVR programs, researchers reported in JAMA Cardiology Dec. 5, suggesting the quality of an institution’s surgical team could be an indicator of how they’ll fare after they initiate TAVR.

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Flu shots improve survival in heart failure patients

Receiving the flu vaccine could improve cardiovascular and all-cause mortality outcomes in patients with heart failure, according to a large-scale study of Danish citizens published Dec. 10 in Circulation.

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Stroke patients see similar odds of readmission with thrombectomy, thrombolysis

About 1 in 8 patients who received endovascular thrombectomy (EVT) for acute ischemic stroke during a two-year period in the U.S. were readmitted to the hospital within 30 days, according to an analysis of the Nationwide Readmissions Database published in JACC: Cardiovascular Interventions.

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‘It wasn’t what you read in pamphlets’: Survivor warns MI symptoms are different in women

One MI survivor is raising awareness for heart attack symptoms in women after her Dec. 9 tweets about an unusual episode went viral.

Ambulatory BP monitoring deemed cost-effective in most scenarios

Ambulatory blood pressure monitoring (ABPM) is cost-saving across nearly all age groups, regardless of whether patients are found to have hypertension on the initial screening, according to a study published in Hypertension.

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Intra-aortic balloon pumps most successful within hour of cardiogenic shock

Patients who present to the hospital with cardiogenic shock (CS) and are treated with an intra-aortic balloon pump (IABP) are more likely to survive if the device is implanted within an hour of CS onset, according to research published in the American Journal of Cardiology Dec. 4.

Mylan expands valsartan recall to all unexpired lots in US

Mylan Pharmaceuticals expanded its voluntary drug recall to include all unexpired valsartan-containing products in the U.S., the FDA announced Dec. 4. The action joins a host of other recalls over the last few months related to carcinogenic impurities being found in angiotensin II receptor blockers (ARBs), a class of medications used to treat hypertension and heart failure.