Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

Medtronic's Evolut Pro TAVR valve treating aortic stenosis

Medtronic TAVR valves at heart of key studies presented during PCR London Valves 2024

One study presented during the three-day conference focused on the potential benefits of an optimized TAVR pathway. Another study, meanwhile, tracked changes in paravalvular leak severity over time.

Newsweek ranked the 50 best heart hospitals in the world

Prosthesis-patient mismatch after TAVR: 5 key findings related to patients with small annuli

PPM is still relatively common after TAVR, especially among patients with a small aortic annulus. What can be done to minimize the risk of PPM? Does valve type play a role? Researchers explored those questions, and many others.

Gilbert H. Tang, MD, professor in the Department of Cardiovascular Surgery at the Icahn School of Medicine and surgical director of the Structural Heart Program at the Mount Sinai Health System, explains how to overcome the limited imaging windows of the tricupid valve using a TEE and intracardiac echo (ICE) at TCT 2024.

How to overcome imaging challenges during tricuspid valve procedures

Gilbert Tang, MD, surgical director of the structural heart program at the Mount Sinai Health System, discussed a key challenge care teams often encounter during tricuspid valve procedures. 

Cardiologist Azeem Latib

First patients treated with Abbott’s new balloon-expandable TAVR valve

Abbott already has an FDA-approved self-expanding TAVR valve, the Navitor system, on the market. The company is now evaluating the safety and effectiveness of a new balloon-expandable device that could potentially be implanted using software guidance. 

Sapien 3 Ultra Resilia TAVR valves

Newest TAVR valve from Edwards linked to better 1-year outcomes than its predecessors

The Sapien 3 Ultra Resilia TAVR valve from Edwards Lifesciences is associated with a significantly higher survival rate after one year than the company's previous balloon-expandable valves. Researchers identified other key benefits as well, sharing their findings in JACC: Cardiovascular Interventions.

doctor examines patient data on their tablet

TAVR technology keeps evolving, improving outcomes without compromising valve performance

Sponsored by Medtronic

TAVR is a go-to treatment for symptomatic severe aortic stenosis in much of the world, thanks in large part to the hard work of research teams that never stop looking for new, innovative ways to make the technology more effective.

Medtronic_Coronary access

Q&A: How supra-annular, self-expanding TAVR valves open up options for future interventions

Sponsored by Medtronic

TAVR procedures have surged more than 30% since 2020, with more than 107,000 patients receiving a new prosthetic valve in 2023 alone. As this trend continues, it’s increasingly important that cardiologists consider the long-term impact on future coronary interventions patients may need.  

bicuspid aortic valve disease TAVR

How TAVR valve choice impacts outcomes when treating type 1 bicuspid AS

Self-expanding and balloon-expandable TAVR valves are associated with comparable success rates and one-year outcomes when treating type 1 bicuspid aortic stenosis. However, each valve type comes with its own advantages and disadvantages.