Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

Michael J. Mack, MD, discusses his team's seven-year update to the PARTNER 3 trial at TCT 2025 in San Francisco.

PARTNER 3 update: TAVR still comparable to SAVR in low-risk patients after 7 years

PARTNER 3 has been one of the most closely watched clinical trials in cardiology for many years now. Michael J. Mack, MD, presented a seven-year update during a packed session at TCT 2025. 

Medtronic Stedi Extra Support guidewire

Medtronic launches FDA-cleared guidewire compatible with multiple TAVR systems

The guidewire was built specifically with Medtronic's own Evolut platform in mind. However, it is also compatible with all other commercially available TAVR systems.

Ancora Heart AccuCinch Ventricular Restoration System heart failure FDA

Transcatheter heart failure implant from Ancora Heart linked to positive 2-year data

The flexible device is attached to the inner wall of the left ventricle during a minimally invasive procedure. It was designed to reduce the size of the left ventricle over time.

biodegradable PFO closure device

New biodegradable PFO closure device shows early potential

Researchers tracked patients for two years, using echocardiography to confirm the devices had completely vanished. Additional studies will still be required.

potential new tariffs on medical devices, imaging equipment, PPE and more

Cardiology groups among the voices concerned about more medical device tariffs

When the Trump administration requested public input on adding more tariffs for PPE and all medical devices, hundreds of public comments were submitted. One common concern among those responses is that healthcare providers could be left with significantly higher costs. 

ASE leading push to revise CPT code for interventional echocardiography

The pressure is on for ASE and other societies to create a new CPT code for the use of interventional echocardiography during structural heart procedures.

heart data AI algorithm cardiologist doctor

Medtronic announces new AI partnership focused on improving TAVR care

Participating TAVR programs will receive AI-powered recommendations courtesy of DASI Simulations.

heart drugs with stethoscope

SGLT2 inhibitors after TAVR may boost survival, limit bioprosthetic valve dysfunction

Prescribing these drugs to TAVR patients could improve certain clinical outcomes, according to a new study of nearly 27,000 adults.