Structural Heart Disease

Structural heart diseases include any issues preventing normal cardiovascular function due to damage or alteration to the anatomical components of the heart. This is caused by aging, advanced atherosclerosis, calcification, tissue degeneration, congenital heart defects and heart failure. The most commonly treated areas are the heart valves, in particular the mitral and aortic valves. These can be replaced through open heart surgery or using cath lab-based transcatheter valves or repairs to eliminate regurgitation due to faulty valve leaflets. This includes transcatheter aortic valve replacement (TAVR). Other common procedures include left atrial appendage (LAA) occlusion and closing congenital holes in the heart, such as PFO and ASD. A growing area includes transcatheter mitral repair or replacement and transcatheter tricuspid valve repair and replacement.

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CKD patients on dialysis face worse TAVR outcomes, including a higher risk of in-hospital mortality

The authors examined data from more than 42,000 patients who received care from 2012 to 2017. 

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FDA announces new recall for extended-release metformin due to contamination

Numerous recalls for ER metformin occurred in 2020. This is the first of 2021.

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In-hospital stroke rates higher after TAVR than MitraClip procedures

Post-discharge stroke rates, however, were similar between the two procedures.

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Edwards evaluating the safety, effectiveness of new mitral valve repair solution

The system was designed to require only one small incision to repair a patient’s mitral valve. 

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An eye on imaging: How to limit radiation exposure during TAVR procedures

Specialists at a high-volume facility in Germany were able to successfully limit radiation dose—and patient outcomes did not suffer. 

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American College of Cardiology, American Heart Association share new recommendations for managing valvular heart disease

The new document, published in both the Journal of the American College of Cardiology and Circulation, highlights the significant progress researchers and clinicians have made in this area in recent years.

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Scientists share new data on how gene mutations lead to congenital heart disease

The analysis explored key gene mutations as they occur in human heart cells. 

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Scientists share breakthrough that could limit heart valve disease, help patients avoid replacement surgery

After 15 years of dedicated research, a cardiologist-led team of scientists thinks their work could dramatically change patient care.