Mitral Valve

The heart's mitral valve is the site of the most surgical valve repairs and valve replacements. After the resounding success of transcatheter aortic valve replacement (TAVR), which now makes up more than 50% of aortic valve replacements, there is wide expectation transcatheter mitral replacements will follow in the next few year. Currently, the most common transcatheter mitral procedure is transcatheter edge-to-edge (TEER) , using the MitraClip or Pascal clip devices. These devices are also being used for transcatheter tricuspid valve repair (TTVR). Other transcatheter mitral repair systems are in trials for minimally invasive annuloplasty and chordae tendineae repair.

Medtronic using AI to identify more TAVR patients in need
Medtronic has launched new research into AI's potential to identify patients with severe aortic stenosis and other worrying symptoms. The company hopes to overcome longstanding health disparities and reach individuals who may otherwise go untreated.
How robotic-assisted mitral valve repair compares to conventional surgery
Costs remain a concern, especially for low-volume centers, but robotic-assisted MV repair is associated with short-term outcomes comparable to more conventional techniques.
LAMPOON before TMVR improves symptoms without complications, long-term data confirm
LVOT obstruction remains a significant complication of TMVR, making the long-term safety and effectiveness of the LAMPOON technique a hot topic in interventional cardiology.
Baseline TR linked to lower quality of life after TAVR, M-TEER—are more interventions the answer?
Patients presenting for TAVR or M-TEER with baseline moderate or severe tricuspid regurgitation were associated with lower post-treatment KCCQ scores and a higher mortality rate. Perhaps treating more of these patients with tricuspid valve repair or replacement could make a difference, researchers noted.
Atrial functional mitral regurgitation: Surgery improves outcomes more than medical therapy alone
"These findings underscore the importance of understanding AFMR and its treatment options," one cardiologist said.

How intravascular lithotripsy can improve TMVR outcomes

The IVL technology developed by Shockwave Medical helped clinicians treat a TMVR patient who had previously undergone TAVR. Could this be a common use of IVL in the future?

January 12, 2023

TEER reduces mitral regurgitation, boosts survival among cardiogenic shock patients

Researchers tracked outcomes data and imaging results from nearly 4,000 TEER patients, sharing their findings in the Journal of the American College of Cardiology.

October 24, 2022

New-onset AFib, linked to worse outcomes and higher healthcare costs, seen in 3.5% of TEER patients

Patients who developed new-onset AFib tended to be sicker than those who did not.

October 7, 2022

The Medtronic Intrepid transcatheter mitral valve replacement (TMVR) system performed well in two studies presendted at TCT 2022. #TCT #TCT22 #TCT2022 #TMVR

Intrepid transcatheter mitral valve pilot study shows positive 3-year outcomes

New data on the Medtronic Intrepid transcatheter mitral valve replacement system from the Intrepid Pilot Study and Intermediate-Term Outcomes of the Intrepid Early Feasibility Study, were presented at the 2022 Transcatheter Cardiovascular Therapeutics (TCT) conference.

September 26, 2022

The Pascal transcatheter mitral valve repair system. Similar to the latest version of the MitraClip, the Pascal can operate each leaflet independently to grasp the mitral valve leaflets. Results of the CLASP IID trial at #TCT2022.

Pascal transcatheter mitral repair device performs as well as MitraClip in late-breaking CLASP IID Trial

Comparison between transcatheter edge-to-edge repair (TEER) devices found Pascal was non-inferior compared with MitraClip in the CLASP IID pivotal trial.

September 20, 2022

he U.S. Food and Drug Administration (FDA) granted market clearance ion September 2022 for the Edwards Lifesciences Corp. Pascal Precision transcatheter valve repair system for transcatheter edge-to-edge repair (TEER). It is indicated for the treatment of patients with degenerative mitral regurgitation (DMR).

FDA clears Edwards Pascal device for transcatheter mitral valve repair

This is the second FDA-cleared transcatheter repair device for the mitral valve. Data from pivotal trial comparing Pascal vs. MitraClip will be presented at TCT 2022.

September 16, 2022

Examples of structural heart transcatheter valve replacement procedure planning CT scans and post procedure followup for TMVR and TAVR.

VIDEO: CT imaging for TAVR and TMVR structural heart interventions

Joao Cavalcante, MD, director, cardiac MRI and structural CT labs, Minneapolis Heart Institute, discusses the use of cardiac CT imaging to plan and guide structural heart procedures.

September 15, 2022

HFpEF patients with MR may face a higher mortality risk—but not if they have AFib

There is an established connection between MR and HFrEF, but we know much less about the link between MR and HFpEF.

September 13, 2022

Mitral Valve

Medtronic using AI to identify more TAVR patients in need

How robotic-assisted mitral valve repair compares to conventional surgery

LAMPOON before TMVR improves symptoms without complications, long-term data confirm

Baseline TR linked to lower quality of life after TAVR, M-TEER—are more interventions the answer?

Atrial functional mitral regurgitation: Surgery improves outcomes more than medical therapy alone